Biomedical subjects

T M Goen

Publications and source records attributed to T M Goen.

6 recordsLinked to original sources

PubMed1991

Peripheral corneal degenerations.

Corneal degenerations are among the most commonly encountered disorders in optometry. They are age-related, asymmetrical deteriorations of the cornea with no developmental or hereditary pattern. Although some corneal degenerations may cause pain and profound loss of vision, most are asymptomatic and visually insignificant. This paper will review the histological development, clinical presentation, and management of various peripheral corneal degenerations.

Aging↗

PubMed1989

Dosage cost analysis in glaucoma management.

After the diagnosis of chronic open-angle glaucoma has been made, and the indications vs. contraindications of each of the potential first-line topical medications have been weighed, what medical therapy should be initiated if the most cost effective form of management is desired? We surveyed 40 pharmacies in four cities and found no statistical difference between the mean annual cost of therapy with timolol maleate (Timoptic), betaxolol (Betoptic), and pilocarpine. Statistically, both dipivefrin (Propine) and levobunolol (Betagan) were found to be more expensive. We also discovered that there are large variations in medication prices between various pharmacies. In order to enhance compliance, optometrists may want to know the pharmacies in their communities that offer antiglaucoma medications at reasonable prices.

Analysis of Variance↗

PubMed1987

Acute posterior multifocal placoid pigment epitheliopathy.

The pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is not fully understood. Some believe it to be a primary dysfunction of the retinal pigment epithelium while others assume that its development follows a choroidal vasculitis. It generally presents as a bilateral condition and shows no sex predilection. The visual prognosis is generally good, though severe and permanent visual loss occasionally occurs. The funduscopic presentation consists of multiple flat, yellow-white lesions of the posterior pole at the level of the retinal pigment epithelium. This paper discusses a case of APMPPE and reviews and summarizes the current literature on this disorder.

Acute Disease↗

PubMed1986

Mid-peripheral hemorrhages secondary to Waldenström's macroglobulinemia.

Waldenström's macroglobulinemia is a progressive neoplastic syndrome of the reticuloendothelial system and is characterized by the presence of monoclonal IgM paraproteins. The ocular manifestations of macroglobulinemia can include mid-peripheral hemorrhages, sludging of blood in the conjunctival vessels, blurred disc margins, exudates in the fundus and serous retinal detachment. Waldenström's macroglobulinemia and its ocular complications are herein presented.

Aged↗

PubMed1986

Cromolyn sodium in ocular allergic diseases.

Cromolyn sodium is a highly effective topical anti-allergenic solution for the treatment of vernal, giant papillary, ragweed, and atopic conjunctivitis. It acts by inhibiting the release of histamine and thereby prevents the inflammatory response by subacute type I hypersensitivity reactions. The following paper reviews the drug action of cromolyn sodium and discusses its value in the treatment of type I ocular allergic diseases.

Biomechanical Phenomena↗

PubMed1986

A comparison of Perkins and Goldmann applanation tonometry.

In a study of 103 eyes, the measurement of intraocular pressure (IOP) was compared between the Perkins hand-held tonometer and the Goldmann slit lamp mounted tonometer. IOP readings from the two instruments were highly correlated (+0.91). Advantages inherent to the Perkins design are also discussed.

Adult↗