T M Healey | PubMed Health

PubMed1989

Penetration of topically applied prednisolone sodium phosphate into human aqueous humour.

Gas Chromatography with Mass Spectrometry (GCMS) was utilised to determine the penetration of prednisolone sodium phosphate into the aqueous humour of human volunteers undergoing routine cataract extraction. Detectable levels of prednisolone were measured in the aqueous humour within 15 minutes. Peak concentrations occurred between 90 and 240 minutes, and the steroid could not be detected in samples taken 10 hours or more after topical administration.

Administration, Topical↗

PubMed1976

Evoked potential audiometry.

A large number of different components of the auditory evoked potential can be recorded from the human scalp using averaging techniques. It is now possible to evaluate with such evoked potential measurements the functioning of the entire human auditory system from the hair cell receptors to the association areas of cortex. This multiplicity of evoked potential components is important clinically since any one component measurement may be the most appropriate for a certain subject at a certain time, and also because the replication of objective audiological findings using more than one testing method allows greater confidence in the results. As well as providing an accurate means of determining the extent of a hearing loss, evoked potential studies can also provide information concerning the type and location of such a defect.

Adult↗