Biomedical subjects
T M Mackenzie
Publications and source records attributed to T M Mackenzie.
Coincidental renal cell and endometrial carcinoma: a case report.
A case of renal cell carcinoma and coexistent endometrial carcinoma is reported. The renal tumor in the lower pole of left kidney was detected by staging preoperative ultrasound scan and was confirmed to be a multilocular cystic renal cell carcinoma. There were two separate foci of moderately differentiated endometrial cancer in the endometrial cavity. Microscopic tumor deposits were also found in the left ovary and the right obturator pelvic lymph nodes. The multicentric involvement of endometrial cavity is uncommon and even rarer is the association with renal cell carcinoma. To the best of our knowledge, this is the first report of an association between renal cell carcinoma and endometrial cancer. This case demonstrates the importance of complete preoperative investigation before any definitive surgery for cancer. Without the abdominal ultrasound scanning, the asymptomatic renal cell carcinoma would probably have been undetected.
Aggressive fibromatosis of the spermatic cord. A typical lesion in a "new" location.
The authors describe a 31-year-old man with a 7 cm aggressive fibromatosis (desmoid tumor) of the spermatic cord presenting as a swelling in the left inguinal area that was excised along with the testis and cord. The desmoid tumor is histologically typical, but such tumors arising primarily from the paratesticular structures have apparently not been previously reported and the diagnosis would not be questioned if it not for the unusual site. This tumor is histologically and immunohistochemically indistinguishable from abdominal wall desmoid tumor, with or without Gardner's syndrome. Desmoid tumors at this location should be distinguished from reactive processes, such as pseudosarcomatous myofibroblastic proliferation (so-called "proliferative funiculitis") and inflammatory fibrous pseudotumor, all of which exhibit fibroblastic/myofibroblastic differentiation. Paratesticular fibrosarcoma and leiomyosarcoma should also be differentiated from desmoid tumor that does not have the metastatic potential of sarcomas. Thirty-four months post-operatively, an 8 cm local recurrence in the remaining portion of the left vas deferens causing left hydroureter and hydronephrosis was detected.
An unusual double pigtail stent story.
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