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T M Sharlaeva

Publications and source records attributed to T M Sharlaeva.

3 recordsLinked to original sources

Thymocyte membrane changes and modifications of interphase death.

A reduction in the rate of interphase death of X-irradiated thymocytes is observed when they are previously treated with triton X-100 or trypsin at low concentrations. The data obtained demonstrate the importance of the structural integrity of the cell surface in the initiation of processes leading to interphase death of lymphoid cells.

Animals↗

[Modification of the interphase death of thymocytes by using colcemid].

The pretreatment of thymocytes by colcemid (0.02 to 0.5 mu g/ml) induces a change in the plasma membrane state, registered by a pyrene fluorescent probe, and a decrease in the interphase cell death after 4 Gy X-irradiation. The authors discuss the role of the cell surface as a trigger initiating death program in irradiated lymphoid cells.

Animals↗