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T Mätzsch

Publications and source records attributed to T Mätzsch.

64 records · Page 4Linked to original sources
PubMed1981

[Alcohol intoxication of children (author's transl)].

This study is based on 116 blood alcohol estimations of intoxicated children up to 14 years of age; all these children recovered after several hours of clinical treatment. In 84 cases the data about the anamnesis, the neurological symptoms, and the clinical course could be evaluated in detail. The average age of children was 10 years; most of them (60%) were 11--14 years old. Sex distribution: 4 male: 1 female. The average blood alcohol concentration was 1.4% at the moment of blood sampling; it ranged between 0.5 and 2.9%. No constant correlation was found between the blood alcohol concentration of the children, their age, sex, and the intoxication symptoms. As a result of this study it may be stated that there seems to be no special intolerance for alcohol during infancy. Specific aspects of the alcohol intoxication of children, i.e., the rapid passage through the stadium of excitation may be explained by the very short drinking time and the relatively large amount of alcohol ingestion combined with no experience about the effects of C2H5OH.

Adolescent↗
PubMed1981

Chronopharmacologic aspects of hexobarbital oxidation rate in rats.

Circadian variations of hexobarbital oxidation rate in rat liver and the relationship to serum corticosterone levels were determined in 324 animals subjected to different lighting regimen and feeding schedules.--Rats maintained under standard light/dark conditions and with free access to food showed a significant circadian hexobarbital oxidase rhythmicity. Inversion of the light/dark cycle and time feeding was followed by significant changes of the 24-h means of hexobarbital oxidation rate as well as of the shape and phasing of the circadian pattern. The animals' response to the experimentally altered environmental conditions did not reveal a predictable relationship between the shape and phasing of the rhythmic patterns of liver hexobarbital oxidase activity and of corticosterone levels in blood serum; the rats subjected to timed feeding showed decreased levels of corticosterone whereas the hexobarbital oxidation rate of the liver was increased.

Alcohol Oxidoreductases↗
PubMed1981

Abdominal trauma during thirty years: analysis of a large case series.

Studies have been made in 1407 patients of the causes, the organs involved and the outcome of injury to the abdomen in patients needing admission to hospital in an area of Southern Sweden, between 1950 and the end of 1979. The proportion of female patients and those aged over 60 increased significantly. The seasonal distribution of the injuries showed significant change, with a drop in the initially high frequency sustained during the summer months. Penetrating injuries were rare, but increased in the 1970s. Road traffic accidents as the cause of abdominal injuries rose to a maximum of 56 per cent in the late 1960s. The numbers of injured organs and the frequency of other associated injuries rose gradually until the mid-1970s, after which there was a slight decrease. The spleen, liver and large blood vessels were the organs which were increasingly often injured. The annual incidence of various visceral injuries per 100 000 population was calculated. The number of patients with a delay of at least 24 hours before operation fell significantly and there was a tendency to shorter hospital stay. The mortality curve showed a peak in the late 1960s.

Abdominal Injuries↗
PubMed1981

Intestinal trauma, Analysis of 101 cases.

Intestinal injuries sustained by 101 Swedish patients during the period 1950-1979 are reviewed. The abdominal trauma was blunt in 78 cases and penetrating in 23. Small-bowel and mesenteric, but not large-bowel, injuries showed increasing frequency. This was associated with rising numbers of motorcar accidents. Injuries to other abdominal organs were found in 56 of the 101 patients, particularly in those with mesenteric or large-bowel trauma. Clear physical signs of intra-abdominal injury led to rapid surgical exploration in most cases, but some operations were performed after relatively long observation. Most injuries, including those in the colon, were treated with primary repair or resection. Decompressive colostomy or exteriorization were rarely performed. Deaths were mainly caused by other factors than the type of operation. The mortality rate (35%) was constant.

Adolescent↗
PubMed1981

Upper gastrointestinal trauma. Analysis of 45 cases of gastric, duodenal or pancreatic injury.

Injuries to the upper gastrointestinal tract occurring over a 30-year period in a geographically well defined region were analyzed. The incidence was low in comparison with other abdominal injuries, but duodenal and pancreatic injuries were increasingly common in the study's last decade. The stomach injuries were mainly caused by penetrating trauma. The duodenal and pancreatic injuries most commonly resulted from road-traffic accidents. Two duodenal injuries were overlooked at the initial exploration, in which the duodenum was incompletely exposed. Anastomotic insufficiency occurred in one of the three patients who underwent duodenal resection. Most of the pancreatic injuries were contusions that could be managed with drainage. The pancreas was severely damaged in five patients, all of whom had multiple intra-abdominal injuries. Three of the five patients died before or during operation.

Adult↗
PubMedDate not supplied

Low molecular weight heparin compared with dextran as prophylaxis against thrombosis after total hip replacement.

The effect of low molecular weight (LMW) heparin given once daily as prophylaxis against venous thrombosis was compared with that of dextran 70 in an open randomised trial of 100 patients undergoing elective total hip replacement. Four patients were withdrawn after randomisation and thus 96 were included in the final analysis. The development of thrombus was surveilled by the 125I fibrinogen test, and positive readings were verified by venography. Nine of 47 patients given LMW heparin developed thromboses (19%) compared with 18 of 49 given dextran (37%) (p = 0.09). Two further patients who received LMW heparin developed thromboses after leaving hospital (clinical signs became apparent on days 13 and 17, respectively), giving an overall rate of thrombosis in this group of 23%. Minor wound haematomas occurred in two of 47 in the LMW heparin group and three of 49 in the dextran group (4% and 6%, respectively), and blood loss, transfusion requirements, and reduction in postoperative haemoglobin concentration did not differ between the two groups. The studied LMW heparin given subcutaneously once a day was no less safe or effective than dextran in preventing thromboembolism after total hip replacement.

Aged↗