Biomedical subjects

T Mairs

Publications and source records attributed to T Mairs.

3 recordsLinked to original sources

PubMed2006

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

An automatic data-collection system has been implemented and installed on seven insertion-device beamlines and a bending-magnet beamline at the ESRF (European Synchrotron Radiation Facility) as part of the SPINE (Structural Proteomics In Europe) development of an automated structure-determination pipeline. The system allows remote interaction with beamline-control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.

Data Collection↗

PubMed2006

Energy-dispersive absorption spectroscopy for hard-X-ray micro-XAS applications.

Originally developed for time-resolved X-ray absorption spectroscopy (XAS), energy-dispersive absorption spectroscopy offers new opportunities for applications such as fluorescence detection and microbeams for scanning probe spectroscopy, thanks to recent developments in both instrumentation and optics. In this context, this paper presents a first example of chemical mapping recorded at ID24, the energy-dispersive XAS beamline at the ESRF. Attributes of this geometry for microanalysis are addressed. Finally, present and future plans are discussed and developed in the light of the evolution of the focal spot on this instrument in the past ten years.

Image Processing, Computer-Assisted↗

PubMed1998

Conserving the coherence and uniformity of third-generation synchrotron radiation beams: the case of ID19, a 'long' beamline at the ESRF.

The lateral coherence length is of the order of 100 micron at the 'long' (145 m) ID19 beamline of the ESRF, which is mainly devoted to imaging. Most of the optical elements located along the X-ray path can thus act as ;phase objects', and lead to spurious contrast and/or to coherence degradation, which shows up as an enhanced effective angular size of the source. Both the spurious contrast and the coherence degradation are detrimental for the images (diffraction topographs, tomographs, phase-contrast images) produced at this beamline. The problems identified and the way they were solved during the commissioning of ID19 are reported. More particularly, the role of the protection foils located in the front end, the beryllium windows, the filters and the monochromator defects (scratches, dust, small vibrations) is discussed.

Journal Article↗