PubMed Health⌕ Search

Biomedical subjects

T Mandecki

Publications and source records attributed to T Mandecki.

9 recordsLinked to original sources
PubMed1992

[Thyroid function in patients during long-term treatment with amiodarone].

Thyroid function was evaluated in 31 patients with disturbances of heart rhythm both before and after 13 months of treatment with amiodarone. An increase in blood serum T4 concentration and transient increase (only during the first three months of treatment) in TSH concentration have been observed in almost all the patients studied. Clinically evident form of hyperthyroidism was found only in one female patient. In two patients the changes in hormone concentrations suggesting hyperthyroidism were not accompanied by clinical manifestations, and in four patients there was no clinical hypothyroidism despite hormone levels suggesting such a state. In addition to the determinations of T3, T4 and TSH also the results of TRH-TSH test played an important role in diagnosing both hypo- and hyperthyroidism.

Adult↗
PubMed1992

[Does the sinoatrial node conduction time depend on heart rate?].

The informations about the dependence of sinoatrial conduction time (SACT) on heart rate (HR) are unequivocal. The aim of the study was to establish if such a dependence really exists. The study group comprised 24 patients (9 women and 15 men) aged 42-71 years, mean 55.8. All the patients presented atrial premature contractions of various etiology. No agents affecting heart electrophysiology were administered until the study was completed. In every patient SACT was estimated by means of the Strauss formula from the 24-hr ecg and from transoesophageal single impulse stimulation. SACT obtained from 24-hr ecg was 156.2 +/- 33.1 ms; whereas the one respectively, calculated from the transoesophageal stimulation was 119.0 +/- 21.0 ms. Despite a significant difference between the results (p less than 0.001), the SACT values obtained with both methods correlated well with each other (r = 0.712; p less than 0.01). The dependence of SACT on basic heart cycle length was observed in 9 pts during 24-h ecg (37.5%). Among these pts SACT was shortened with higher and lengthened with lower HR. In the remaining 15 pts this dependence didn't occur, neither it occurred in any patients examined with the single impulse stimulation. The results suggest that the dependence of SACT on HR is not a constant phenomenon and that it occurs only in a part of the examined population.

Action Potentials↗