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Biomedical subjects

T Matsuki

Publications and source records attributed to T Matsuki.

At least 91 records · Page 5Linked to original sources
PubMed1986

[The hand and environment--physiological changes of digital functions in adult men by vibratory stimulations, water immersions and climatic conditions].

Skin temperature, 125 Hz vibratory sensibility and pinch strength of the hand were recorded continuously in adult men through water immersion tests ((1) 40 degrees C (2) 15 degrees C (3) 10 degrees C) and vibratory stress tests ((1) 32 Hz-2 g (2) 32 Hz-3g (3) 125 Hz-2 g) in climatic chambers ((1) 20 degrees C-50% humidity (2) 20 degrees C-50% (3) 30 degrees C-40% and 80%). As a stressor to the hand, the cold water immersion was the most effective. The warm water immersion was effective to slightly decrease the skin temperature and the vibratory sensibility. The younger group showed higher sensitivities of the digital functions than the older group.

Adult↗
PubMed1986

Quantitative histology of peritumoural low density area associated with glioma on CT; image analyzing study of peritumoural low density area after steroid-osmotherapy.

In this study, an invasive site of the tumour cells was quantitatively investigated in the low density area (LDA) on computerized tomography (CT) after steroid and osmotic drug therapy (SOT) by using a texture image analyzing computer system (TAS). Twenty six patients with gliomas (10 benign, 16 malignant) were applied in this study. According to the effect to reduce the volume of LDA, patients were classified into three groups as follows; good, poor, and failed. The reduction effect of the low density volume was not significantly different between the benign and malignant gliomas. Cells including those with a large nucleus with 6.8-9.1 microns in diameter were not observed in the control group, but they were observed in the adjacent and distant parts from the centre of the enhanced tumour element in the peritumoural LDA with 0.87-0.99 percent of all cells in both the poor and failed groups. But in the good group they were significantly rarely observed in the peritumoural LDA after SOT (p less than 0.05). Furthermore, they were significantly frequently observed in the adjacent part from the centre of the enhanced tumour element in the peritumoural LDA with 0.9 percent of all cells after SOT in the malignant gliomas in comparison with the benign gliomas (p less than 0.05). Conclusively it was suggested that the treatment of glioma with peritumoural LDA on CT must be extended to the adjacent and distant part from the centre of the enhanced tumour element in the peritumoural LDA as well as the treatment of the enhanced tumour mass on CT in the poor and failed groups.

Adolescent↗
PubMed1984

[Psychiatric symptoms of patients with chronic subdural hematoma].

Thirty-two cases with chronic subdural hematoma in adults were analyzed from two standpoints; one is the characteristics of pre- and post-operative psychiatric symptoms, the other is the common factors in patients with post-operative psychiatric symptoms. The average age of subjects was 55.4 years, and psychiatric symptoms were noticed in 18 cases (56%). Main pre-operative psychiatric symptoms were disorders of intellectual capacity including memory and orientation disturbance and were able to be classified into amnestic syndrome and dementia according to DSM-3. Outcome in amnestic group was good in contrast to that in dementia group mostly complicated by post-operative psychiatric symptoms. Post-operative psychiatric symptoms were seen in 6 cases. The average age of these cases was 68.2 years which was higher than that of asymptomatic group. And these were classified as dementia according to DSM-3. Common factors in these 6 cases were as follows: Accompanied by marked pre-operative psychiatric symptoms. High age. Complicated by post-operative subdural fluid collection with certain mass effects. Long period from head injury to operation. Accompanied by other complications such as cirrhosis of liver and hypertension. Subdural fluid collection following surgery is a problem under discussion. We obtained favorable results by subdural-peritoneal shunt.

Adult↗
PubMed1983

[Case of hepatocellular carcinoma with a marked reduction in the tumor size induced by PSK administration alone].

A 56-year-old man was admitted to our hospital because of right abdominal pain. The edge of the liver was felt 4.5 fingers breadth below the xiphoid process. AFP was 20100 ng/ml and CEA was 5.6 ng/ml. The chest X-ray indicated existence of lymphangitis and some nodular density suggesting lung metastasis in the both lower-lung fields. 99mTc-phytate liver scan showed a large defect along the antero-inferior margin of the right hepatic lobe, which revealed an abnormal uptake of 67Ga-citrate. Ultrasonograms demonstrated a solid mass, 8 X 9 cm, in the right lobe of the liver. A CT-scan of the abdomen also showed a large, rounded, low attenuation mass with central necrosis in the right hepatic lobe: the pancreas and the remaining retroperitoneal structures appeared normal. Following the administration of PSK alone, 3 g daily, for three months, a remarkable regression of both hepatomegaly and lung metastasis was observed. Liver scan, ultrasonograms and CT-scan showed a striking resolution of the intrahepatic mass except central necrosis. AFP decreased to 33.7 ng/ml and CEA was 8.2 ng/ml. After about one year, however, ultrasonogramms showed a newly growing solid mass, 3.5 X 3.5 cm, in the left lobe of the liver. A needle biopsy specimen was taken from the intrahepatic mass, and it was interpreted as hepatoma. He is now healthy.

Carcinoma, Hepatocellular↗
PubMed1983

[Clinical significance of measurement of immunosuppressive acidic protein (IAP) in lung cancer].

Immunosuppressive acidic protein (IAP) was investigated in 37 patients with lung cancer. A positive rate of IAP in patients was 62.2% and it was higher than that in pulmonary benign diseases except infectious cases. Serum IAP levels increased in accordance with the progress of disease, but no relationship with histological findings was observed. No significant correlation was found between serum IAP levels and in vivo PPD skin test. However, in patients with more than 1000 micrograms/ml of serum IAP levels, higher proportion of patients with negative PPD skin test was observed, indicating the depressed immunity of these patients. From these results, it was suggested that the effects of treatment and prognosis could be predicted by pre-and post-operative IAP levels.

Adult↗
PubMed1983

The hand and environment (5):--Physiological changes of digital functions in two age groups studied by three stress tests under three environmental conditions.

Our serial physiological studies on "the hand and environment" have been reported these last three years. As a stressor to the hand, cold water immersion was the most effective, and the lower the room temperature was, each stressor became the more effective. As a detector for the function of the hand, the digital temperature was the most valuable. However, for studying the digital temperature, the room temperature should be set at more than 20 degrees C. The counting numbers were reduced by aging and colder temperatures. The nerve conduction velocity SCV or MCV became slower in a colder room, but showed no differences between the two age groups in this study.

Adult↗
PubMed1982

The hand and environment (3)--physiological changes of digital functions in two age groups studied by vibratory stimulations and a cold water immersion.

Skin temperature, vibratory sensibility and pinch strength of the hand were recorded continuously in 20 healthy adults through two vibratory stress tests (32 Hz and 125 Hz) and a cold water (10 degrees C) immersion (for 10 min) test in a climatic chamber (20 degrees C, 50% humidity). As a stressor to the hand, the immersion was the most effective and the vibrator stress at 32 Hz was next. As a detector for function of the hand, vibratory sensibility at 125 Hz was proved to be the most valuable and the digital temperature was the next. As to aging, the mature age group showed low vibratory sensibilities at 63 Hz, higher digital temperatures, stronger pinch strengths, and quicker recoveries after the stress tests. Along the passage of time after entering the chamber, the vibratory sensibilities and the pinch strengths did not show any changes. However, the digital temperatures became continuously lower.

Adult↗
PubMed1982

Alteration of NADH-diaphorase and cytochrome b5 reductase activities of erythrocytes, platelets, and leucocytes in hereditary methaemoglobinaemia with and without mental retardation.

NADH-diaphorase and cytochrome b5 reductase activities of platelets and leucocytes, as well as erythrocytes, were found to be deficient in a patient with hereditary methaemoglobinaemia associated with moderate mental retardation and non-progressive neurological disturbance, in which hyperactive reflexes and involuntary movements were notable. In another methaemoglobinaemic patient with no mental or neurological abnormalities, these enzyme activities were defective in erythrocytes but normal in platelets and leucocytes. The first case was a generalised cytochrome b5 reductase deficiency with non-progressive encephalopathy. It is suggested that the detection of cytochrome b5 reductase activity in platelets, in addition to that in leucocytes, is useful for the assessment of a generalised enzyme defect. Genetical involvement of the present cases is discussed in association with the diaphorase gene loci in humans.

Adolescent↗
PubMed1982

G6Pd Kanazawa: a new variant of glucose-6-phosphate dehydrogenase associated with congenital nonspherocytic hemolytic anemia.

A new variant of G6PD associated with chronic nonspherocytic hemolytic anemia (CNSHA) in a Japanese male is described. This variant is unique in that it has a normal electrophoretic mobility, normal Km for glucose-6-phosphate and NADP, and a normal utilization of the substrate 2-deoxyglucose-6-phosphate and deamino-NADP. It also shows a decreased thermal stability and a biphasic pH curve. These characteristics distinguish this variant from previously reported variants associated with CNSHA and we have called it G6PD Kanazawa.

Adult↗