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Biomedical subjects

T Mehedinţi

Publications and source records attributed to T Mehedinţi.

9 recordsLinked to original sources
PubMed2006

Correlated histological and morphometric study of kidney and adrenal gland from Guinea pig exposed to hyperbaric-hyperoxic environment.

Our study revealed morphological changes in the two organs of Guinea pig kidney and suprarenal gland exposed to hyperbaric-hyperoxic environment. Proceeding from these data and knowing that in hyperbaric-hyperoxic environment the production of free oxygen radicals is increased, while the afferent arterioles undergo vasoconstriction, with direct implications on the cellular metabolism, our study puts forth the survey of the influence of hyperoxic environment on kidneys and adrenal gland - complex organs which are exposed to stress.

Adrenal Cortex↗
PubMedDate not supplied

Histological and histochemical alteration in certain Black Sea bivalves submitted to accidental pollution.

Due to their microphage capacity, two-valve shells have great biologic importance: they clean the environment of harmful microorganisms and decaying organic compounds which result in water purification, water filtering by means of adaptive structures of digestive system and, indirectly, by those of respiratory, circulatory and excretive system is of major significance. Waste materials derived from animal metabolism coalesce in larger aggregates which sink and deposit onto the bottom, thus enabling the bivalvular shells to contribute to developing and securing adequate conditions for the productive cycle of marine environment and even twining themselves into food for animals. Our study makes a histological, histochemical and histometric survey of branchia (ctenidia) of Mytilus galloprovinciallis so as to enlarge the scant body of knowledge on the topic in reference literature.

Animals↗
PubMedDate not supplied

Aspects of the cell population in the skin of the guinea pig exposed to hyperbaric-hyperoxic environment.

Knowing that in hyperbaric-hyperoxic environment, the production of free oxygen radicals is increased, with the direct implications on cellular metabolism, our study follows the influence of the hyperbaric environment, a very complex organ that is exposed to directly to this environment. We used a group of 10 guinea pigs split into to lots (test and control lots). The test lot was exposed for consecutive days to an ambient pressure of 6 ATM for a period of 30 min. After 50 days both groups was given lethal doses of pentobarbital, afterwards skin was harvested and fixed into Bouin's fluid and formaline, than paraffin embedded. The slides stained with Haematoxylin-Eosin and trichromic Van Gieson. The epidermal fields examined by us revealed no significant variations of nuclear number, though the mean saturation of nuclei was significantly greater in test animals than in the control group, while the nuclear area fraction was higher in the control group. The melanin load of the epidermal cells was increased in the control animals. The presence of intraepidermal vacuoles was identified, their amount being almost double in test animals than in the control group.

Adaptation, Physiological↗
PubMedDate not supplied

Structure of the osseous callus formed under electric stimulation. An experimental histological study.

The study tried to evidence histologically, histometrically and mechanically the comparative qualities of the osseous callus experimentally formed in dogs and rabbits under the influence of an electric stimulation. The materials were decalcified or polished, and the collagen network and the Haversian systems analysed in the callus. The tearing strength in kg-power on the surface unity of the osseous tissue was measured using the EDZ 20 apparatus. The results indicated that the osseous tissue formed under electric stimulation had a structure and a tearing strength similar to that of controls, and that the consolidation time of fractures is reducing.

Animals↗
PubMedDate not supplied

Epithelial mesenchymal interrelations at the skin level. A quantitative study.

Epithelial mesenchymal interrelations at the skin level were quantitatively studied by analysing the modifications of fibrocytes in the framework of total connective cells and capillaries of the dermic mesenchyme and of the number of mitoses in the epidermis. A normal group of guinea pigs was compared with a massaged one (II) and a massaged one using ointment (III). There were found significant differences between the elements of the first and those of the second and third groups, and no significant differences between the 2nd and the 3rd ones. There were established and compared the ratio of dermal fibrocytes to other connective cells, to dermal capillaries and to epidermal mitoses: the ratio remained similar in all groups. These results lead to the conclusion that dermis (expressed by its cells and capillaries) and epidermis (reflected in mitoses) have a correlated response to the mechanical action exerted in physiological limits, and that the epithelial mesenchymal dependence at the skin level is determined by the strong interrelations which are not easily modifiable.

Animals↗