Biomedical subjects

T Mendel

Publications and source records attributed to T Mendel.

6 recordsLinked to original sources

PubMed1992

Neural elements in human cervical intervertebral discs.

This study attempted to characterize neural elements within the human cervical intervertebral disc. Cervical intervertebral discs were obtained from four adult human subjects at autopsy. Discs were stained in bulk with gold chloride, sectioned, and viewed with the light microscope. Nerve fibers appeared to enter the disc in the posterolateral direction and course both parallel and perpendicular to the bundles of the anulus fibrosus. Nerves were seen throughout the anulus but were most numerous in the middle third of the disc. Receptors resembling Pacinian corpuscles and Golgi tendon organs were seen in the posterolateral region of the upper third of the disc. These results provide further evidence that human cervical intervertebral discs are supplied with both nerve fibers and mechanoreceptors.

Adult↗

PubMed1992

Anticardiolipin antibodies, a disease marker for ischemic cerebrovascular events in a younger patient population?

The prevalence of anticardiolipin antibodies (ACLA) in sera of 49 patients having had their first TIA or ischemic stroke before 50 years of age was studied using a solid phase enzyme immunosorbent assay (ELISA). Five patients had IgM antibodies, eight had IgG, and three had antibodies belonging to both classes. Although ACLA were detected in 32% of patients (95% confidence interval [CI] 19-45%), the ACLA positive group did not differ with respect to clinical characteristics and distribution of major stroke risk factor frequency from the ACLA negative group. Further investigations are needed to establish the role of ACLA in the pathogenesis of ischemic cerebrovascular diseases.

Adult↗

PubMed1992

Endarterectomy for symptomatic carotid stenosis. Review of the European and North American Symptomatic Carotid Surgery Trials.

The recent results of two major multicenter trials, ECST (European Carotid Surgery Trialists') and NASCET (North American Symptomatic Carotid Endarterectomy Trial), show benefit of carotid endarterectomy for patients with recent (4-6 months), nondisabling, carotid distribution, cerebral ischemic events (hemispheric and retinal TIA or stroke) and ipsilateral severe (70-99%) carotid stenosis provided that perioperative mortality remains low. ECST, in addition, failed to demonstrate the benefit of surgery for patients with mild stenosis (0-29%). The comparisons between the studies in regards to methodology, measurements, and complications are discussed.

Carotid Stenosis↗

PubMedDate not supplied

[Demonstration of cardiac arrhythmias in multi-infarct dementia and ischemic stroke using Holter monitoring].

The occurrence of the cardiac arrhythmias was estimated by using 24-hour ECG Holter monitoring in 30 patients with multi-infarct dementia and in 30 with ischaemic stroke. Holter monitoring revealed pathological cardiac arrhythmias in 36.7% patients with multi-infarct dementia and in 40% with single ischaemic focus in the brain. It also allowed to reveal more frequent occurrence of cardiac arrhythmias in patients with ischaemic stroke (40%), than standard ECG (17%).

Adult↗

PubMedDate not supplied

[Ischemic stroke in patients under 50 years of age with special reference to its etiology and risk factors].

Eighty-four patients with ischaemic stroke aged 18-50 years were analysed. They had been treated in the years 1985-1989. Forty-five of them were followed up. In a high proportion of cases stroke was a result of thrombosis. Many risk factors were found in this group, mainly hypertension. In most cases stroke was serious, in several cases post-stroke epilepsy and poly-infarction dementia developed.

Adolescent↗

PubMedDate not supplied

[Hemodilution in the treatment of cerebrovascular disorders].

Haemodilution includes intravenous administration of plasma-replacing solutions and/or blood letting for changing the rheological properties of blood, and for improvement of microcirculation. Three methods of haemodilution various plasma substitutes are given: dextran, hydroxyethyl starch (HES), electrolyte solutions (e.g. Ringer's solution, normal saline, 5% glucose, colloidal plasma, protein solutions), plasma, albumins. The controversial results of clinical trials of the method for therapeutic purposes are discussed. In the light of the reports as yet, it seems that the best results are obtained using normovolaemic haemodilution with administration of HES.

Blood Volume↗