Increase in multiresistance of Shigella dysenteriae type 1 strain in Rwanda.
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Anti-Bacterial Agents↗
Biomedical subjects
T Mets
Publications and source records attributed to T Mets.
Rheumatoid arthritis and tuberculosis in Africa.
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Adolescent↗
Similarity between in vitro and in vivo cellular aging.
In vivo and in vitro cellular aging were compared by determining the division capacity of individual, cloned cells of (1) the primary stromal population of human bone marrow, obtained from donors of various ages, and (2) the population at various passage levels of an in vitro subcultivated culture of the same origin. We find a strong similarity between the two series of data. This observation provides a further argument that cellular aging in vitro represents a biologically relevant phenomenon.
Adult↗
Variations in the stromal cell population of human bone marrow during aging.
Age-related variations in the stromal cell population of human bone marrow were studied by means of a cloning assay. It was found that these cells are heterogeneous both in division capacity and in morphology. Fibroblast-like progenitor cells could be distinguished from epithelial-like cells, having only a very limited division potential. A significant inverse correlation between the donor age and the number of progenitor cells could be demonstrated. This loss of progenitor cells during aging was compensated by an increase in the number of epithelial-like cells.
Adolescent↗
In vitro aging of human bone marrow derived stromal cells.
We have studied the in vitro cellular aging process in human bone marrow derived stromal cells. Two cell types, here called type I and type II, can be distinguished in the primary cell population. During subcultivation, resulting in aging in vitro, the type I cells gradually disappear, whereas the type II cells form an increasing fraction of the population. This observation is confirmed by cloning experiments, revealing that type I cells act as progenitor cells, giving rise to non-dividing type II cells. These results are best explained by the terminal differentiation theory as proposed by Martin et al.
Adult↗
A 2 year experience with percutaneous renal biopsy under ultrasonic guidance.
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Biopsy, Needle↗
Strong, intravascular reflections revealed by real-time sonography in some large vessels.
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Blood Circulation↗
[Determination of the biological age of man: study of the relevance of the in vitro aging process of fibroblasts].
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Adolescent↗
Sonically guided renal biopsy.
The results of 91 sonically guided renal biopsies are reported. In the 53 cases where renal size and function allowed other localization techniques, renal tissue was obtained in 100 percent and glomeruli in 88.6 percent. In 38 cases no other techniques could have been used because of poor renal function (serum creatinine greater than or equal to 4.0 mg/dl) and/or decreased renal size (less than or equal to 10 cm); in these biopsies renal tissue was obtained in 86.8 percent and glomeruli in 73.7 percent.
Biopsy, Needle↗
Increased prostaglandin F2 alpha and E2 production in late passage WI38 diploid fibroblasts.
The prostaglandin (PG) F2alpha and E2 concentrations in the culture medium of WI38 cells were determined at various passage levels. It was found that late passage cells produce significantly higher amounts of both PG F2alpha and PG E2.
Cell Line↗
Real-time ultrasonography of the normal pancreas in young adults: advantage of the erect position.
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Adult↗
The theory of transition probability and the division pattern of WI--38 cells.
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Cell Cycle↗
Lipid-lowering effects of procetofene.
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Adult↗
Pseudomyxoma peritonei. Report of a case with extraperitoneal metastasis and invasion of the spleen.
The findings in a patient with pseudomyxoma peritonei, probably of appendicular origin, are reported. As a rule, pseudomyxoma peritonei remains limited to the peritoneal cavity, but in this case, dissemination occurred to the right pleural cavity and to the pericardium. In addition, invasion of the spleen (to our knowledge, nor previously described) was noted.
Appendiceal Neoplasms↗
[The significance of muramidase (lysozyme) determinations in hematologic diseases].
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Adult↗
[Acute gastrointestinal hemorrhage: etiology, prognostic factors and course in 90 patients treated in an intensive care unit].
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Adolescent↗
Clostridium difficile infection in a geriatric ward.
In a prospective, longitudinal study we searched for the presence of Clostridium difficile in the stools of 100 consecutively hospitalized elderly patients (mean age: 82; SD: 9.5 years). C. difficile was found on admission in 6 patients, 3 of whom were asymptomatic carriers. Ten patients acquired C. difficile during hospitalization. Four different types of C. difficile were isolated. The various types were clustered in time, indicating that the infection was acquired from the environment.
Journal Article↗