This paper presents a family case of brother and sister with unilateral lymphedema, set off spontaneously at prepuberty and earlier in the boy. They both developed a unilateral chylothorax at the age of 22-24. No congenital anomalies are present. The clinical and paraclinical data exclude forms of secondary lymphedema as well as the ones associated with gonadal dysgenesis. The family case history reveals that the parents are not kindred, appear healthy, without pulmonary complaints. Neither no other cases similar to the patients described nor other congenital anomalies or genetic diseases have been recorded in the family. The peculiarity of the cases consists in the fact that lymphedema is confined only to the left lower limb and that there are no modifications in the parents, suggesting an autosomal recessive transmission, which would be a pathogenic novelty. The association with chylothorax points to the importance of a thorough evaluation of the patient with lymphedema of the lower limb.

Adult↗

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[Neurosarcoidosis. Comments on 2 cases].

Sarcoidosis can involve any tissue in the body and, consequently, the disease presents to clinicians of many different disciplines. We report two cases of sarcoidosis involvement of the nervous system: one male patient with right facial nerve palsy and a cutaneous involvement (supraorbital subcutaneous nodule) associated with bilateral hilar adenopathy; and a female patient presenting a hypothalamus involvement with diabetes insipidus, obesity, lethargy, sleep disturbances and amenorrhoea. In the later case an upper respiratory tract involvement was also present with nasal and tonsils sarcoidosis. A review of the clinical manifestations of neurosarcoidosis and the criteria for establishing the diagnosis is presented.

Adult↗

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[The 160th anniversary of the Society of Physicians and Naturalists of Iaşi].

Explore the source record for details and available documents.

History, 19th Century↗

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[Percutaneous pleural drainage].

The paper reports on the technique of percutaneous pleural drainage. The advantages of the method are discussed: the technique of the percutaneous pleural drainage is superior to the repeated thoracenteses with needle; it has several advantages versus pieurotomy, in the case of pneumothorax and of the serofibinous pleurisy.

Catheterization↗

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[The efficacy of the intensive, short-duration chemotherapy of patients with cavitary pulmonary tuberculosis].

This study was carried out on 100 cases of cavitary pulmonary tuberculosis in patients eliminating tuberculosis bacilli, as noted at microscopic study. The treatment included four drugs (RHSZ) in 95 case, and 3 drugs in the remaining patients. All the treatments were tailored to individual needs. The duration of chemotherapy was of 6 months in 62 cases. It was prolonged to 9 months in 33 cases and to 12 months in 5 cases. In 81 patients the drugs were applied regularly. The results have demonstrated that at 6 months negative cultures were obtained in 98 patients although the excavations were closed in only 55 cases. At 9 months all the patients were negative but excavations were closed in only 71. Suppression of elimination of bacilli was achieved in 99 of the cases at 12 months, but the excavations were closed in only 92 of the patients. Ninety-nine patients were investigated after 2.5-3.0 years. Five of them were again positive, 94.5% were negative and the excavations were closed in 91.9%. The importance of the cavitary score is discussed with regard to the risk of renewed positivity, and an association is recommended of surgical collapsing and exeresis at the right time.

Adult↗

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[Variations in plasma angiotensin-converting enzyme and renin in sarcoidosis].

A comparative study of plasma angiotensin-converting enzyme and renin activity was carried out in 55 patients with sarcoidosis and other pulmonary diseases. The converting enzyme activity was significantly increased in active sarcoidosis, showing a tendency to return to normal values after corticoid treatment, while plasma renin activity remained unaltered both before and after corticotherapy. The obtained results confirm the usefulness of the converting enzyme measurements, as already shown by others. Attention is drawn on the possible involvement of the pulmonary renin-angiotensin system in the local vascular and enzymo-chemical alterations, suggesting the possibility of associating the converting enzyme inhibitors to the corticotherapy of sarcoidosis.

Fluorometry↗

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