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Biomedical subjects

T Minarík

Publications and source records attributed to T Minarík.

5 recordsLinked to original sources

[Interatrial and atrioventricular conduction in dual chamber stimulation].

SAMPLE AND METHODOLOGY: 111 patients (54 men) with atrioventricular stimulation of an average age 56.5 +/- 14.3 were examined. Permanent cardiostimulation was indicated in 56 patients for sick sinus syndrome and in 55 patients for complete AV blockade. Average LV EF was 52.1 +/- 5.7% and LA endsystolic dimension was 39.8 +/- 4.0 mm. All patients were done esophageal electrocardiography under synchronous atrioventricular stimulation regimen. Values of interatrial conduction were compared in relation to placement of stimulation electrode in atrium. RESULTS: Interatrial conduction in the whole sample was 79.8 +/- 19.5 (40-150) ms, for placement of an electrode in heart auricle, in lateral or in anteroseptal wall of the right atrium it was 79.9 +/- 17.9 ms, 108.3 +/- 16.3 ms, 61.5 +/- 16.2 ms. Difference between programmed AV interval and AV interval set up via esophageal electrocardiography was 40.9 +/- 19.7 (5-95) ms. Value of interatrial conduction in the monitored sample depended on placement of the electrode in atrium and the size of the left atrium (r = 0.24, p < 0.009). We did not prove relation of the interatrial conduction value to LV EF or indication diagnosis. CONCLUSION: Interatrial conduction affects value of the real AV interval in atrioventricular stimulation, depends on placement of stimulation electrode in atrium and on the size of the left atrium. Interatrial conduction can be assessed via esophageal electrocardiography.

Atrioventricular Node↗

[Non-invasive programmed transthoracic ventricular stimulation].

In 10 healthy volunteers programmed transthoracic stimulation of the ventricles was performed using two commercially available non-invasive pacemakers. The connection of the oesophageal stimulator SP-5 with the transthoracic ventricular stimulator NP-4D made it possible to obtain a two-lead ECG tracing without artefacts. The quality of the obtained tracings (surface tracing and oesophageal tracing) made it possible to assess accurately the ventriculo-atrial conduction. The examinations performed indicate the practical use of combined oesophageal and transthoracic stimulation during non-invasive diagnosis.

Adult↗

[Long-term effect of drug therapy in supraventricular dysrhythmia evaluated by diagnostic esophageal cardiac pacing].

The authors investigated the long-term therapeutic effect in 33 patients after a medicamentous reversal of recent atrial fibrillation and 18 patients after reversal of an attack of supraventricular tachycardia (SVT). None of the patients had signs of cardiac failure. A change to sinus rhythm was achieved in the group with atrial fibrillation by digoxin with verapamil, in the group with SVT by verapamil. Treatment was then adjusted, based on testing by means of diagnostic oesophageal pacing. The basic drug for long-term use in atrial fibrillation was digoxin either as monotherapy or in combination; the majority of patients with SVT had verapamil treatment. At the end of the period 24.5 +/- 8.4 (12-36) months after the reversal in the group with atrial fibrillation 8 (25.8%) had permanent atrial fibrillation or different therapy on account of atrial fibrillation; short-term attacks of palpitation were recorded during the investigation period in 16 (51.6%), and the remaining 7 patients (22.6%) had no complaints. In the group with SVT none of the patients was hospitalized on account of persisting dysrhythmia and it was not necessary to alter treatment. Testing treatment of supraventricular dysrhythmias by means of diagnostic oesophageal pacing is of prognostic importance and the authors consider it the method of choice.

Atrial Fibrillation↗

[Noninvasive evaluation of hemodynamics in changes in the atrioventricular interval in patients with dual-chamber pacemakers].

The authors evaluated in 19 patients with Dual Chamber pacemakers, using pulsed Doppler echocardiography, changes of the cardiac output after stimulation type DDD with an A-V interval of 100, 150, 175 and 200 ms. They evaluated also haemodynamic changes when changing the stimulation programme type DDD to ventricular stimulation type VVI. The group of patients was characterized by a left ventricular ejection fraction of 50.3 +/- 9.1%, a dimension of the left atrium of 37.1 +/- 5.6 mm and a end diastolic left ventricular dimension of 52.8 +/- 3.9 mm. The highest values of the cardiac output were recorded in 11 patients with an A-V interval of 175 ms, in 7 patients at 150 ms and in one patient at 200 ms. The difference of the cardiac output between the haemodynamically optimal and pessimal A-V interval assessed for individual patients during stimulation type DDD was 15.5 +/- 9.5%. The difference of the cardiac output during a change of stimulation type DDD with a haemodynamically optimal A-V interval to ventricular stimulation type VVI was 22.8 +/- 8.3%. Doppler echocardiography is a satisfactory non-invasive method for the evaluation of haemodynamic changes when assessing optimal parameters in patients with multiprogrammable dual chamber pacemakers.

Adult↗

[Testing the effectiveness of drug therapy in supraventricular dysrhythmias using diagnostic esophageal cardiac stimulation].

The authors examined 33 patients aged 59.9 years with a new atrial fibrillation and 18 patients aged 45.6 years with attacks of supraventricular tachycardia. After medicamentous change to a sinus rhythm (in fibrillation after digoxin and verapamil i.v. and in supraventricular tachycardia after verapamil i.v.) the patients were changed to oral antiarrhythmic drugs. The method of diagnostic oesophageal stimulation was used after saturation with the oral form to test the effectiveness of long-term treatment. In the author's opinion the basic drug in atrial fibrillation is digoxin, possibly combined with verapamil or quinidine. In supraventricular tachycardia the basic drug is verapamil, in particular in case of a double AV node pathway. In the majority of patients combined treatment is indicated, selected individually by means of diagnostic oesophageal stimulation. The authors consider the described method due to its innocuous and repeatable character as the method of choice for optimization of antiarrhythmic treatment of supraventricular dysrhythmias.

Adult↗