PubMed Health⌕ Search

Biomedical subjects

T N Krupina

Publications and source records attributed to T N Krupina.

At least 19 recordsLinked to original sources
PubMed1980

[Clinical picture and activity of nervous system mediators during chronic modeling of certain factors involved in space flight].

Results of examining the functions of the nervous system and the activity of blood neuromediators after a long-time (182 days) antiorthostatic hypokinesia are presented. It has been shown that along with polymorphic clinical signs on the part of the nervous system (hemodynamic disturbances, asthenoneurotic manifestations, neuromuscular, metabolic, trophic, and vegetovascular disturbances, signs of insufficient training of the cardiovascular system, stato-kinetic and pain phenomena) undulating changes of the neuromediator activity reflecting the course of compensation and adaptation processes in the conditions of long-time hypokinesia are observed.

Adaptation, Physiological↗
PubMed1976

A study of the cumulative effects of repeated exposures to radial accelerations.

After exposure to transverse accelerations of 4-10 g changes in the vascular system of the eye and immunobiological resistance of the body persisted from 5 to 15 days. The data give evidence that the state of retinal vessels is the most informative index of the cumulative effect on the body and its recovery.

17-Hydroxycorticosteroids↗
PubMed1976

Effect of antiorthostatic bed rest on the human body.

Head-down (-4 degrees) bedrest brings about a more rapid development of changes in haemodynamics, fluid displacement and nervous tone than traditional recumbent bed rest. Changes occurring during head-down hypokinesia have much in common with the changes typical of real weightlessness. They are characterized by phasic changes in the vascular tone. Under these conditions changes in the tone and blood-filling of the brain are important for the functional state of the vestibular apparatus.

Adaptation, Physiological↗
PubMed1975

[Cytogenetic analysis of the effect of cosmic flight factors on man].

The results of cytogenetic investigation of 14 crewmembers of "Soyuz" spacecrafts before and after 7 spaceflights are represented. No cytogenetic changes were noted at the investigated crewmembers on the first postflight day as compared to the preflight data. Possible causes of differences between the author's data and the data of foreign investigators on cytogenetic investigation of American crewmembers are discussed in the article.

Adult↗
PubMedDate not supplied

[State of vascular regulation and regional hemodynamics in the crew of "Soiuz-12" and "Soiuz-13" spaceships before and after flight].

Postflight rheographic examinations carried out at rest and during postural tests showed noticeable changes in the vascular regulation and significant blood redistribution. On the recovery day there were no signs of the intracranical venous congestion to weightlessness. The tone of cerebral vessels, however, increased to prevent the development of cerebral venous congestions during the antiorthostatic test. This may be a result of weightlessness adaptation. These cerebral hemodynamic reactions were more pronounced in the crewmembers who made an 8-day flight than in those who made a two-day flight, i. e. in the cosmonauts who returned to Earth after weightlessness adaptation.

Arm↗
PubMedDate not supplied

[Comparative evaluation of studies of the action of different levels of hypoxia on the human immunobiological status].

The effect of hypoxic hypoxia on the specific factors of immunity of 16 test subjects was studied during their 30-day exposure to an altitude of 2100-4200 m above the sea level in the area of the Elbrus mountain. In order to differentiate the effect of hypoxia per se from that of other factors typical of highlands, five runs of altitude chamber experiments were carried out. In each run the test subjects were 10 times lifted to altitudes of 3200 m, 4200 m and 5200 m. The chamber experiments were performed on 28 test subjects, aged 26-46. During an exposure to an altitude the test subjects did two or three times exercises of 450-900 kgm/min on a bicycle ergometer. The experimental findings show that hypoxic hypoxia brings about consistent changes in the immunobiological status of man that are directly correlated with the level of hypoxia. These changes include a decline in the acquired antiviral and antitoxic immunity activation of the autoimmune process and an increase in the phagocytic activity of neutrophils. Our results suggest optimal profiles of the hypoxic effect to which test subjects should be exposed during mountain training for a specific occupational activity.

Acclimatization↗