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T N Oniani

Publications and source records attributed to T N Oniani.

At least 37 records · Page 2Linked to original sources
PubMed1972

Electrical activity of the hippocampus during delayed responses and hypothalamic stimulation in the cat.

Electrical activity of hippocampus was investigated in cats in the delayed response situation by comparing spectral analysis and integration of electrohippocampogram rhythms in different stages of delayed response performance. In addition, electrical stimulation of lateral and ventromedial hypothalamic nuclei was used to observe changes in the hippocampal theta rhythm, as well as the behavioral effect during the delayed response performance. It is concluded that changes in the hippocampal theta rhythm are related to the changes in the drive level: high drive results in increasing the theta rhythm, whereas drive reduction results in its suppression. The activating role of hypothalamus in the dynamic changes occurring in the limbic circuit and their function in solving the delayed response problem are widely discussed.

Animals↗
PubMed1972

Effects of cingulate cortex lesions on emotional behavior and delayed responses in cats.

Bilateral thermocoagulation of the cingulate gyri produced an abolishment of fear reactions concomitantly with an exaggerated aggressiveness and a drastic impairment of delayed responses. The changes in emotionality subsided after several months but there was no recovery, even after prolonged post-operative training, of the dalayed responses with a 5 min delay. Only partial improvement of the responses with shorter delays (10 sec and 1 min) was observed. This memory deficit is discussed in terms of disruption of neuronal limbic circuits necessary for maintaining the impulse reverberation.

Aggression↗
PubMedDate not supplied

Influence of some monoamine oxidase inhibitors on the sleep-wakefulness cycle of the cat.

The influence of some monoamine oxidase inhibitors (phenelzine, transamin [tranylcypromine], nialamide) on the structure of the sleep-wakefulness cycle of the cat was studied. It was shown that these monoamine oxidase inhibitors elicit and increase in slow-wave sleep in the sleep-wakefulness cycle due to complete suppression of paradoxical sleep and significant decrease in wakefulness. After the cessation of the action of the monoamine oxidase inhibitors, a selective rebound of wakefulness is observed against the background of complete or partial absence of paradoxical sleep. The gives grounds for the hypothesis that during partial deprivation of wakefulness under the influence of monoamine oxidase inhibitors an intensification occurs on the accumulation of specific need for this physiological state, the satisfaction of which is accomplished as the result of its rebound in the post-deprivational cycle, i.e., after the termination of the EEG of the synchronizing effect of the monoamine oxidase inhibitors.

Animals↗
PubMedDate not supplied

[The possibility of elaborating conditioned reflexes on the basis of emotional reactions evoked by electrical stimulation of limbic structures].

In experiments on cats with chronically implanted electrodes a conditioned stimulus (200 c/s tone) was paired with electrical stimulation of limbic structures, which produces pronounced emotional behaviour: defensive, aggressive, alimentary or drinking reactions. It has been shown that conditioned reactions are not elaborated on the basis of electrical stimulation, which activates alimentary, drinking or aggressive behaviour. Neither is a conditioned reflex formed to the combination of sound and stimulation of the brain structures, which inhibits alimentary behaviour. A distinct conditioned fear reaction sets in as a result of combination of sound and electrical stimulation of brain structures, which evoke defensive behaviour. The data obtained are analyzed in the light of the significance of natural requirements of the organism for the elaboration of conditioned reflexes.

Aggression↗