Biomedical subjects

T N Sollertinskaia

Publications and source records attributed to T N Sollertinskaia.

At least 19 recordsLinked to original sources

PubMed2002

[Opioid mechanism of regulation of the autonomic and motor functions in rabbits].

In rabbits, effects of s.c. administration of met-enkephaline (MET) and stimulation of hypothalamic nuclei upon vegetative and motor functions are similar and involve changes of the breathing rate, heart rate, and diminishing of the motor component of orienting responses. MET acts mainly upon cardiac parameters. Administration of naloxone eliminates the MET effect upon the vegetative and motor parameters. The role of opioid mechanism in regulation of the brain's visceral-motor function regulation, is emphasized.

Animals↗

PubMed1996

[The comparative physiological characteristics of the regulating effect of vasopressin on higher nervous activity in mammals in an ascending order].

Small doses of vasopressin in hedgehogs facilitated positive conditioning as well as formation of extinguishing inhibition. In rabbits [correction of rodents], vasopressin enhanced the trace conditioning however shortly. In monkeys, vasopressin exerts a complicated effect upon simpler conditioning and memory processes, the conditioned memory being obviously enhanced.

Acoustic Stimulation↗

PubMed1995

[A comparative study of the role of ACTH and beta-endorphin in regulating the conditioned-reflex activity of hedgehogs].

The ACTH was shown to facilitate learning and to enhance the memory processes in hedgehogs. Administration of beta-endorphin enhanced the latency of conditioning, exert an analgetic effect, reduced the motor and intersignal activities, as well as eliminated the inhibitory effects of the limbic cortex stimulation. Different influences of the ACTH and beta-endorphin upon the higher nervous activity as well as possible mechanisms of these effects, are discussed.

Acoustic Stimulation↗

PubMed1992

[The role of dermorfin in regulating hibernation processes in mammals].

Administration of dermorphin (0.1 mg/kg, subcutaneously) induced a drop of body temperature, deceleration of initial vegetative parameters and development of hibernation-like state in susliks. The delayed effects involved a disorder in conditioning. The immunisation of hibernating susliks with the dermorphin conjugate leads to a gradual waking up of the animals, normalising of conditioning in all the parameters and occurrence of a motor component in avoidance conditioning. A possible specific role of the dermorphin in the mechanisms of hibernation, is discussed.

Acoustic Stimulation↗

PubMed1991

[The effect of the opioid neuropeptides: met-enkephalin and beta-endorphin on the conditioned reflex activity of hedgehogs].

The effect of opioid neuropeptides was found to be more obvious in functional pathology of the higher nervous activity in hedgehogs. Met-enkephalin exerted a more obvious and longer-lasting effect on complicated forms of nervous activity, particularly inherent those. Naloxone abolished the met-enkephalin effect. The comparative effect of different opioid neuropeptides on inherent and acquired forms of nervous activity in mammals, the correlation between structural distribution of the neuropeptides and their functional properties, are discussed.

Acoustic Stimulation↗

PubMed1990

[The role of beta-endorphin in regulating the conditioned reflex activity of cats].

The role of beta-endorphin in regulation of instrumental food conditioning and in more complicated forms of nervous activity in cats was found to involve a facilitating unspecific effect both on positive and negative food conditioning, the latter having a general adaptive character. The influence of the same small doses of beta-endorphin (10 mkg/kg - 15 x 10(-6) mkg/kg) on the choice responses was more complicated and depended on the basic level of conditioning and the typology of animals. Possible mechanism of the beta-endorphin effect on higher nervous activity, is discussed.

Animals↗

PubMed1990