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T Nanea

Publications and source records attributed to T Nanea.

10 recordsLinked to original sources
PubMedDate not supplied

[Nuclear stethoscopy. The clinical technic, methods and applications].

The paper reports on a new way of cardiological, radionuclidic investigation of the patients, a technique used for the first time in Romania. The technique and investigation method are presented in detail, with emphasis on some more important stages. As resulting from the description of the methodology, the performances of the left ventricle consist of three types of radioactivity/time curves at: first passage, beat by beat, and their summation. Of the advantages offered by the nuclear stethoscope, mention should be made that, besides the evaluation of systolic and diastolic parameters, it monitors the left ventricle functions in the rhythm disturbances, beat by beat, and being mobile, it permits the investigation at the patient's bed. Finally, the paper presents several cases investigated by the authors, and their special clinical applicability.

Coronary Disease↗
PubMedDate not supplied

Level of ventricular myosin light chains 1 and 2 determined by ELISA in serum of patients with acute myocardial infarction.

The serum level of human ventricular myosin light chains 1 and 2 was determined by competitive ELISA assay in 56 patients, of whom 26 with acute myocardial infarction (18 with simple AMI and 8 with complex AMI), 10 with unstable angina pectoris and 20 healthy subjects. The serum level of human ventricular myosin light chains 1 and 2 (HVMLC1 and HVMLC2) in healthy subjects was of 6-10 ng/ml. Sensitivity of the assay was 10 ng/ml, and the working range was 10-100 ng/ml. In all AMI patients the HVMLC1 serum level exceeded 2-3 times the reference range within the first 24 hours after the onset of chest pain, the mean (+/- ISD) peak concentration was of 45.7 (+/- 13.6) ng/ml (simple AMI) and 64.22 (+/- 18.5 ng/ml) (severe AMI) 48 hours after infarction and it remained significantly higher than the normal value for another 7-10 days after the onset of infarction. The serum HVMLC2 concentration exceeded 10 ng/ml 48 hours after infarction, with a mean (+/- 1SD) peak concentration of 37.8 (+/- 10.4) ng/ml (simple AMI) and 53.8 (+/- 16.1) ng/ml (complex AMI) 90 hours after the onset of infarction and remained at high values for another 4-7 days. In two of ten patients with unstable angina pectoris LC2 increases above 10 ng/ml. The prolonged release of HVMLC1 and HVMLC2 in serum for 4-7 days after the onset of myocardial infarction may facilitate the retroactive detection of infarction, hence the extension of myocardium necrosis.

Creatine Kinase↗