Biomedical subjects

T Nitatori

Publications and source records attributed to T Nitatori.

48 records · Page 3Linked to original sources

PubMedDate not supplied

Improvement of MR cholangiopancreatography at .5 T: three-dimensional half-averaged single-shot fast spin echo with multi-breath-hold technique.

The purpose of this study was to determine the advantage of a three-dimensional (3D) single-shot fast-spin-echo (SSFSE) sequence to obtain MR cholangiopancreatography (MRCP) with a .5-T MR unit by comparison with a two-dimensional (2D) SSFSE sequence. MRCP with 2D-SSFSE and with 3D-SSFSE with 128 echo train lengths was performed on 15 volunteers and 38 patients with pancreatobiliary disease using a .5-T MR unit. For maximum intensity projection (MIP) reconstruction, the section thickness of source images was 4 mm in the 2D-SSFSE and 3 mm in the 3D-SSFSE. 3D volume data in 3D-SSFSE were obtained using repeated short breath-hold of 2 seconds for every repetition time throughout the examination. The image quality, duct conspicuity, signal-intensity ratio (SIR), and contrast-to-noise ratio (CNR) were evaluated. In 23 of the patients who underwent both MRCP and direct cholangiopancreatography (endoscopic retrograde cholangiopancreatography [ERCP]/percutaneous transhepatic cholangiography [PTC]), a comparison between these two modalities was also conducted. The image quality of the MIP image with 3D-SSFSE (49 of 53, 92.5% graded excellent or good) was superior to that with 2D-SSFSE (31 of 53, 58.4%). Duct conspicuity, SIR, and CNR were significantly higher with 3D-SSFSE than with 2D-SSFSE. 3D-SSFSE also showed a stronger relationship with the ERCP/PTC findings compared to 2D-SSFSE. 3D-SSFSE provided satisfactory quality, SIR, and CNR of MRCP images, even when a .5-T MR unit was used, because the breath-hold technique used during 3D data sampling minimized all types of motion effects.

Adolescent↗

PubMedDate not supplied

Diffusion-weighted MR imaging with single-shot echo-planar imaging in the upper abdomen: preliminary clinical experience in 61 patients.

BACKGROUND: To determine the potential ability of diffusion-weighted magnetic resonance (MR) imaging with single-shot echo-planar imaging (DW imaging) in the upper abdomen by apparent diffusion coefficient (ADC) and signal:intensity ratio (SIR) measurements. METHODS: DW imaging was performed in 61 clinical patients. ADCs in the liver, pancreas, spleen, kidney, and different pathological conditions were calculated. Spleen-to-liver SIR and segmental intensity difference of the liver (SID) were also calculated. RESULTS: The mean ADCs (mm(2)/s) were 2.28 x 10(-3) +/- 0.07 in the liver, 1.44 x 10(-3) +/- 0.05 in the spleen, 1.94 x 10(-3) +/- 0.19 in the pancreas, and 5.76 x 10(-3) +/- 0.06 in the kidney. The mean ADC of cirrhotic liver was 1.96 x 10(-3) +/- 0.62, which was lower than that of normal liver. Other pathologic conditions also showed ADCs different from those of normal tissues. All DW images showed significantly higher spleen-to-liver SIRs and SIDs than did T2-weighted images (p < 0.05). CONCLUSION: The mean ADCs obtained with DW imaging were different in each upper abdominal organ and with each pathologic condition. DW images showed better soft tissue contrast than did T2-weighted images with regard to SIR and CNR in depicting and characterizing upper abdominal disorders.

Adult↗

PubMedDate not supplied

CT of calcified chronic aortic dissection simulating atherosclerotic aneurysm.

Calcification along the outermost aspect of the aorta usually means atherosclerotic aneurysm. On occasion, however, this peripheral type calcification is seen in chronic aortic dissection and leads to a misdiagnosis. Conventional chest roentgenography and CT of 50 cases of chronic dissection proven by angiography were reviewed. Four of these cases (8%) showed calcification in the outermost wall of the affected portion of the aorta. Two cases were Stanford type A and the other two cases were type B. In type A cases chest roentgenography showed calcification in the wall of the dilated ascending aorta closely mimicking aneurysm. In type B cases, calcification was in the outer wall of a localized hump in the descending aorta. Computed tomography clearly demonstrated that this peripheral calcification was located in the outermost wall of the false lumen. Review of the pathologic literature shows sporadic reports of such phenomenon and a theory of endothelialization of the false lumen. It is presumed that the endothelialized false lumen may develop atheromatous changes much more rapidly than the true lumen since two of four cases showed calcification only in the wall of the false lumen with the intimal flap and the wall of the true lumen remaining noncalcified.

Aged↗

PubMedDate not supplied

Breath-held MR cholangiopancreatography with half-averaged single shot hybrid rapid acquisition with relaxation enhancement sequence: comparison of fast GRE and SE sequences.

PURPOSE: Our goal was to determine whether half-averaged single shot hybrid rapid acquisition with relaxation enhancement (single shot hybrid RARE) sequence can improve image quality, duct conspicuity, signal intensity ratio (SIR), and contrast-to-noise ratio (CNR) of MR cholangiopancreatography (MRCP) by comparing it with two other MRCP sequences: fast SE (FSE) and contrast-enhanced Fourier-acquired steady-state technique (CE-FAST). METHOD: MRCP with three sequences was obtained in 46 people (10 volunteers, 36 patients with pancreatobiliary disease). Overall image quality and duct conspicuity were graded. SIR and CNR were also measured. RESULTS: Overall image quality was graded excellent or good in all 46 patients (100%) with single shot hybrid RARE, in 38 of 46 (83%) with FSE, and in 5 of 46 (11%) with CE-FAST. Duct conspicuity was the best in single shot hybrid RARE statistically. SIR was the highest in FSE, while CNR was highest statistically in single shot hybrid RARE of three sequences. CONCLUSION: Single shot hybrid RARE can provide consistently higher quality MRCP than FSE and CE-FAST because sequential images by single shot hybrid RARE minimize respiratory, bowel, and cardiac motion artifacts.

Adolescent↗

PubMedDate not supplied

Fast dynamic MRI of aortic dissection: flow assessment by subsecondal imaging.

PURPOSE: The aim of this study was to evaluate fast dynamic MRI, which consists of a subsecondal MRI sequence combined with a rapid contrast medium infusion technique, in examining clinical cases of aortic dissection. MATERIALS AND METHODS: The subjects consisted of 27 patients with aortic dissection. Turbo-FLASH imaging of the aorta was conducted to obtain 50 image frames within 40 seconds. RESULTS: Recognition of the intimal flap and differentiation of the true channel from the false channel was easily accomplished in all 15 patients with a patent false channel. The entry site was detected in 13 of 15 patients. Differentiation of slow flow from thrombus in the false channel was possible in all 27 cases, and the relationship between the lesion and the main branches of the aortic arch was identified in 26 of 27 cases. CONCLUSION: Fast dynamic MRI may provide a large amount of information that is useful for the diagnosis of aortic dissection.

Aortic Dissection↗

PubMedDate not supplied

MRI artifacts of metallic stents derived from imaging sequencing and the ferromagnetic nature of materials.

In vitro and in vivo studies were performed to assess the optimum materials and imaging methods for metallic stents by conducting an in vitro investigation of MRI artifacts arising during imaging by several representative imaging methods using various types of stents and by clarifying the differences occurring with different metals and imaging sequences. We also examined the use of MRCP and MRA in evaluating luminal patency within stented biliary tracts and blood vessels in vivo. In vitro study showed either no artifacts or very slight artifacts created by titanium stents, however, marked image distortion was created by a stainless steel stent. Using SE instead of GRE sequences can minimize these artifacts. Echo planar imaging (EPI) produced severe susceptibility artifacts, resulting in unsatisfactory images. In vitro and in vivo studies indicated that MRCP was an effective method for follow-up studies of bile duct stents, but that MRA is quite limited as a method of follow-up study for currently available vascular stents.

Aged↗

PubMedDate not supplied

Clinical application of single shot GRE-EPI as non-enhanced MRA (EPI-MRA) for aortic aneurysm and dissection.

We investigated the usefulness of single shot gradient echo type echo planar imaging (GRE-EPI) as magnetic resonance angiography (MRA) for the diagnosis of aortic aneurysm and dissection. This technique can detect blood flow signals in several tenths of a milliseconds without the need for contrast medium, breath-holding, or electrocardiographic (ECG) gating. By scanning approximately 20 frames in the coronal plane, three-dimensional (3D) imaging can be achieved by maximum intensity projection (MIP) at different angles. Three radiologists evaluated the ability of this single shot GRE-EPI as non-enhanced MRA (EPI-MRA) to diagnose aortic aneurysm and dissection. The examined lesions consisted of three cases of thoracic aortic aneurysm, seven of abdominal aortic aneurysm and eight of aortic dissection with a total of 15 involved aorta. In all patients with aortic aneurysm, EPI enabled detection and diagnosis of the aneurysm. However, the size of the lesion and relationship with major branches were determined only in the abdominal aorta, and could not be determined precisely in thoracic lesions. Similar results were obtained for patients with aortic dissection. The technique visualized the intimal flap and enabled determination of the extent of dissection in the abdominal aorta. In the thoracic aorta, serious magnetic susceptibility artifacts caused image distortion, and as a result only the dissection could be detected and diagnosed. No entry site was detected at either the abdominal or thoracic aorta. These results suggest that EPI-MRA may have a clinical potential for screening patients with acute aortic disease who cannot undergo physical restraint for scanning.

Aged↗

PubMedDate not supplied

Non-contrast enhanced MR venography using 3D fresh blood imaging (FBI): initial experience.

OBJECTIVE: This study examined the efficacy of 3D-fresh blood imaging (FBI) in patients with venous disease in the iliac region to lower extremity. MATERIALS AND METHODS: Fourteen patients with venous disease were examined [8 deep venous thrombosis (DVT) and 6 varix] by 3D-FBI and 2D-TOF MRA. All FBI images and 2D-TOF images were evaluated in terms of visualization of the disease and compared with conventional X-ray venography (CV). RESULTS: The total scan time of 3D-FBI ranged from 3 min 24 sec to 4 min 52 sec. 3D-FBI was positive in all 23 anatomical levels in which DVT was diagnosed by CV (100% sensitivity) as well as 2D-TOF. The delineation of collateral veins was superior or equal to that of 2D-TOF. 3D-FBI allowed depiction of varices in five of six cases; however, in one case, the evaluation was limited because the separation of arteries from veins was difficult. CONCLUSION: The 3D-FBI technique, which allows iliac to peripheral MR venography without contrast medium within a short acquisition time, is considered clinically useful.

Adult↗

PubMedDate not supplied

MR imaging of the breast with Gd-DTPA enhancement: comparison with mammography and ultrasonography.

The accuracy of MR imaging with Gd-DTPA enhancement was compared with mammography and ultrasonography in 52 patients with clinically palpable benign and malignant breast masses (36 carcinomas, 2 malignant phyllodes tumors, 7 fibroadenomas, 7 cysts). On dynamic MR imaging, carcinomas and fibroadenomas were discriminated by their different dynamic enhancement profiles. In carcinomas, signal intensity increased rapidly, reaching a peak or plateau within 2 min after the injection of contrast medium. In fibroadenomas, signal intensity showed a much slower continuous increase without ceasing until about 8 min after injection. Malignant phyllodes tumors showed a dynamic enhancement profile identical to that of benign fibroadenomas. MR imaging correctly identified 84% of malignant tumors, 86% of fibroadenomas, and 100% of cysts, and was substantially more accurate in tissue characterization than mammography. The results of ultrasonography were highly similar to those of MR imaging. However, no single modality was infallible, and the three modalities were complementary rather than competitive. Considering the high cost and long examination time of MR imaging, mammography supplemented by ultrasonography seems to be the method of choice in the diagnosis of breast lesions. Nevertheless, MR imaging can add important information when the results of mammography and ultrasonography are insufficient or contradictory.

Adenofibroma↗

PubMedDate not supplied

Femoral arterial thrombosis in nephrotic syndrome. Steroid and long term heparin therapy.

Thrombosis due to increased coagulability of the blood is a common complication in patients with nephrotic syndrome. Thrombosis has a tendency to recur in these patients. We recommend steroid and long term heparin therapy after thrombectomy for the prevention of the recurrence of thrombosis in nephrotic patients and for the control of nephrotic syndrome. This report deals with two cases of femoral arterial thrombosis complicated by nephrotic syndrome. In one case the result was not satisfactory despite usual postoperative treatment, while the other case was successfully treated by long term heparin infusion in combination with oral administration of steroid.

Adult↗

PubMedDate not supplied

Atelectasis as a complication of tracheobronchial stent therapy.

Although insertion of expandable metallic stents in cases of tracheobronchial stenosis is effective as palliation for respiratory distress, the potential risk of creating obstructive atelectasis and aggravating symptoms of patients should be noted. The authors' experience in two cases is presented, and prevention of this potential complication is discussed.

Adult↗

PubMedDate not supplied

Fast MR imaging of abdomen: application of the QD body coil and low refocusing flip angle.

The fast spin-echo (FSE) method as applied to abdominal imaging has undergone considerable technical and clinical study over the past several years. However, except in a limited number of institutions, this time-saving sequence has not replaced the conventional spin-echo (CSE) method. In particular, FSE is less frequently employed for examination of the liver because FSE and CSE images of hepatic tumors and normal hepatic tissues differ significantly in terms of contrast. The signal reduction effect of magnetization transfer contrast (MTC) is affected by the number of slice sections and by the specific absorption rate (SAR). We have employed a newly developed quadrature detection (QD) body coil to enhance the signal-to-noise ratio (S/N) and a low refocusing flip angle to suppress SAR and MTC effects. We have also evaluated the effectiveness of this new method by carrying out visual assessment of clinical images and quantitative measurements of signal intensity in these images. Several problems must be overcome before the FSE method is able to replace the CSE method in the clinical examination of the abdomen. The selection of sequences with a low refocusing flip angle combined with the use of the QD body coil promises to be one possible solution to these problems.

Abdomen↗