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T Oba

Publications and source records attributed to T Oba.

130 records · Page 8Linked to original sources
PubMedDate not supplied

Translation in vitro of codon UGA as tryptophan in Mycoplasma capricolum.

The in-frame UGA codons in the synthetic messenger RNA were translated in the cell-free system of Mycoplasma capricolum. The result, together with the occurrence of codon UGA at tryptophan sites in the genes and the presence of tRNA(UCATrp) pairing with UGA, clearly indicated that UGA is a tryptophan codon in this bacterium.

Base Sequence↗
PubMedDate not supplied

Heterogeneity of phospholipase C in the cochlea of the guinea pig.

In the present study, we investigated the presence of phosphatidylinositol-specific phospholipase C (PLC) isoforms in the cochlea of the guinea pig using Western blot analysis and immunocytochemistry. By Western blotting, PLCbeta1 and delta1 were expressed in the cochlear sensory epithelia (CSE) and PLCbeta1, gamma1 and delta1 were expressed in the cochlear lateral wall. By immunocytochemistry of the CSE, PLCbeta1-like immunoreactivity was mainly expressed in the outer hair cells (OHCs), but not in the inner hair cells (IHCs). PLCgamma1 and delta1 were expressed neither in the OHCs nor in the IHCs. In the cochlear lateral wall, PLCbeta1, delta1 and gamma1 were expressed in the stria vascularis and the spiral ligament. In addition, PLCbeta1, delta1 and gamma1 were also present in type I spiral ganglion cells. Based on these results, we discussed the function of these PLC isoforms in the cochlea.

Animals↗