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T Odori

Publications and source records attributed to T Odori.

At least 19 recordsLinked to original sources

Clinical results and development of variable-stiffness video colonoscopes.

BACKGROUND AND STUDY AIMS: This study was designed to assess the usefulness of variable-stiffness video colonoscopes, compared with conventional videoscopes. PATIENTS AND METHODS: The first prototype XCF-QAY1 and the latter prototype XCF-Q240A1 used in this study can be varied to 4 levels of stiffness of tube insertion during examination. In 352 consecutive colonoscopic examinations performed using these and two conventional scopes, the following data were recorded: time for intubation to the cecum, frequency of changes in the patients' posture, frequency of abdominal pressure attempts, and pain score. The degree of stiffness of the insertion tube and the examiners' impressions score were recorded only in procedures where the variable-stiffness scopes were used. RESULTS: There was no significant difference between colonoscopes in the pain score. Total colonoscopy rate was 97.4%. The frequency of usage of the varying stiffness control in the colon according to site was as follows: descending colon, 57.3%; transverse colon, 32.8%, sigmoid colon, 7.6%; and ascending colon, 2.3%. A significant difference in the mean time for intubation to the cecum between the XCF-Q240A1 and conventional scopes was observed. Moreover, there were significant differences in the frequency of abdominal pressure attempts and changes in the patient's posture between conventional scopes and the new scopes. CONCLUSIONS: These results suggest that only one scope, the XCF-Q240A1, is needed for any colonic examination by any examiner.

Aged↗

[Transient ischemic dilatation of the left ventricle observed on dipyridamole-stressed thallium-201 scintigraphy].

To assess clinical significance of transient ischemic dilatation of the left ventricle (TID) on dipyridamole-stressed 201Tl myocardial scintigraphy, 110 patients suspected with coronary artery disease, including 13 with normal coronary, 48 with single vessel disease, 30 with 2 vessel disease, and 19 with 3 vessel disease were analyzed. TID was visually and quantitatively assessed calculating the ratio of the area within the left ventricular region on the initial and delayed image (TID ratio). TID was observed in 3 of 1 vessel disease (6%), 5 of 2 vessel disease (17%), and 8 of 3 vessel disease (42%). None of normal coronary artery showed TID. In patients with multivessel disease (MVD), TID was observed more frequently (27%) than in patients with 1 vessel disease (6%) (p < 0.025). Furthermore, the TID ratio tended to be higher (1.15 +/- 0.11) than those with single vessel disease (1.03 +/- 0.03). To identify patients with MVD, TID had a sensitivity of 27% and a specificity of 95%. ECG changes were observed more often in patients with TID than those without TID. Five patients showing TID underwent coronary artery bypass graft surgery, TID disappeared postoperatively in each patient. In conclusion, TID on dipyridamole 201Tl scan seems to be a specific although not sensitive marker for detecting MVD.

Adult↗

[Clinical value of thallium-201 reinjection after delayed imaging in patient showing incomplete or no redistribution].

To asses clinical value of Tl-201 (Tl) reinjection after delayed imaging, 30 patients who showed incomplete or no redistribution in stress-delayed Tl myocardial scintigraphy were studied. Of 76 myocardial segments with incomplete or no redistribution on the delayed images, 29 segments (38%) showed improvement of Tl uptake after Tl reinjection. Reinjection was considered effective in 24 segments (32%) where no or little redistribution were observed on the delayed images but improved after reinjection. The contrast ventriculography showed less wall motion abnormality in the segments with improvement after reinjection than that without improvement after reinjection (regional wall motion score: 2.55 +/- 0.50 vs. 0.59 +/- 0.97 p less than 0.01). History of myocardial infarction was also significantly less in the former (p less than 0.05). We conclude that Tl reinjection is useful in cases showing no or equivocal redistribution on the delayed images.

Coronary Disease↗

[Diagnostic ability of various biopsy needles].

We compared the diagnostic ability of various biopsy needles. A liver of an anesthetized rabbit was biopsied using 8 needles for cytology (23G, 22G, 21G Spinal; 23G, 22G, 21G Chiba; 22G Westcott; 22G Rotex II) and 12 needles for histological core biopsy (21G, 18G Sonopsy; 23G, 21G, 19G, 17G Sure-cut; 21G Majima; 18G, 16G, 14G Quick-cut; 14G Tru-cut; 18G Roth-biopsy). The volume of the recovered cells was not dependent on the bore of the needles for cytological biopsy (21-23G). However, the volume of the recovered tissue was dependent on the bore of the needles for core biopsy (14-23G). 22G Westcott needle and 22G Rotex II needle both showed excellent ability to obtain large amount of cells. 21G Sure-cut needle and 21G Majima needle both could obtain enough volume for histological diagnosis.

Animals↗

[New devices for non-vascular interventional radiology].

Interventional Radiology (IVR) is a field of medicine, which has made diagnosis or treatment previously performed only by surgery possible percutaneously. For safe and successful IVR, good devices are necessary. Therefore, development of new devices is essential for the progress of IVR. Various kinds of new devices for non-vascular IVR are introduced, including new biopsy needles, AccuStick, Cope Gastrointestinal Suture, Rösch-Thurmond Fallopian Tube Catheterization Set, ESP Glove and others. Most of them are now commercially available in Japan. However, all of them cost much higher than they cost in the USA.

Humans↗

[Intravoxel incoherent motion (IVIM) imaging using an experimental MR unit with small bore].

IVIM images were constructed from a pair of spin echo (SE) sequences on a 2T MR unit with small bore. In the current study, two types of SE were used: the standard SE and the other sensitized to microscopic incoherent motion by adding motion probing gradient on either side of 180 degrees pulse. IVIM images of water and acetone phantoms were generated, and the diffusion coefficients obtained from these materials were consistent with the literature values. IVIM images of implanted human tumor in nude mouse showed relatively high apparent diffusion coefficient (2.0 x 10(-3) mm2/sec). However, in the sacrificed mouse, diffusion coefficient in the tumor was markedly decreased (0.5 x 10(-3) mm2/sec), which suggested the considerable contribution of perfusion to ADC. In conclusion, IVIM imaging was thought to be highly valuable because it can provide functional information about tumor perfusion.

Animals↗

[Percutaneous ethanol injection of parathyroid adenoma under US guidance].

A patient with post-operative recurrent parathyroid adenoma was treated with percutaneous injection of absolute ethanol under ultrasonographic guidance. Serum calcium and PTH level were both successfully normalized, while recurrent nerve palsy was encountered as side effect. Six months later, she was suffered from hyperparathyroidism again, because of local tumor recurrence. Her recurrent nerve palsy was cured at that time. This technic could be a simple and non-invasive alternative for the conventional surgical procedure, but the indication for larger adenomas like this case should be carefully considered.

Adenoma↗

Centripetal spread of arterial collateral endothelial cell hyperplasia after renal artery stenosis in the rat.

The factors responsible for collateral arterial growth after major artery occlusion remain obscure, despite their importance for tissue survival. An increase in endothelial cell labelling with tritiated thymidine, as an index of collateral arterial growth, occurs early after renal artery occlusion. Our working premise was that an increase in endothelial cell labelling would occur simultaneously throughout the length of the collateral arteries if biophysical factors related to blood flow were the responsible mechanism, because blood flow must be increased simultaneously throughout the length of the small, preformed collateral arterial vessels. On the other hand, if the information spread from the ischemic zone, one would anticipate centripetal spread of the endothelial cell hyperplasia in a retrograde direction from the ischemic zone. With the periureteric collateral arterial supply as the model, we performed serial studies of tritiated thymidine labelling following renal artery stenosis in the rat. As anticipated, endothelial cell labelling rose sharply within 24 to 48 hours, first evident in the area immediately adjacent to the renal hilum. Thereafter, a progressive, time-related centripetal gradient in endothelial cell tritiated thymidine labelling occurred (p less than 0.01). These findings indicate that the factors responsible for endothelial cell hyperplasia are less related to blood flow in the lumen than to downstream, ischemic events. Although the mechanism responsible for the centripetal spread remains speculative, the communication system is likely to involve cell-to-cell contact in the vessel wall.

Animals↗

A quantitative assessment of scintigraphy of the legs using 201Tl.

201Tl perfusion scintigraphy of the legs was evaluated to define intermittent claudication quantitatively, based on Sapirstein's indicator fractionation principle. After intravenous injection of 201Tl with or without exercise, the distribution of the radiotracer throughout the body was obtained using the whole blood scanner. Regional blood flow of cardiac output for three segments of the leg was estimated as a regional fractional uptake (rFU) distributed in these segments compared with the whole body distribution. The validity of the principle was confirmed by a comparative study with 99mTc-MAA (r = 0.979). Normal rFUs (%) for each section at rest and after stress, respectively, were 5.49 +/- 0.69 and 19.40 +/- 2.04 (whole leg); 3.57 +/- 0.49 and 12.26 +/- 1.91 (thigh); 1.59 +/- 0.34 and 6.58 +/- 0.61 (calf). The rates of rFU change from the state of rest to stress (delta rFU) in normals were 3.41 +/- 0.45 (whole leg), 3.44 +/- 0.61 (thigh), and 4.30 +/- 1.03 (calf). Although rFU was within normal limits in patients with arteriosclerosis obliterans (ASO) and thromboangitis obliterans (TAO), delta rFU of the whole leg was significantly decreased from the normal value of 3.41 +/- 0.45 to 1.95 +/- 0.40 for ASO (P less than 0.001) and 1.82 +/- 0.47 for TAO (P less than 0.001). A defect or decreased activity on the stress scintigraph was well correlated with the angiographic findings.

Adult↗