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T Ohsugi

Publications and source records attributed to T Ohsugi.

35 records · Page 2Linked to original sources
PubMed1991

[Study of influence of respiratory rate to airway resistance in patients with pulmonary emphysema].

Application of the panting method is very difficult for patients with pulmonary emphysema (PE). We attempted to measure airway resistance (Raw) during quiet breathing and changing respiratory rate step by step in patients with PE using a pressure-type body plethysmograph system (BX-82) correcting measured values by temperature and humidity. Influence of the respiratory rate to Raw was studied at 0.5l/sec of inspiratory and expiratory flow. Whenever the respiratory rate was going up, the Raw increased in spite of the increase of the thoracic gas volume. Raw (2Hz) was about one and a half times as high as Raw (quiet breathing). On the other hand, when the respiratory rate was going up, elevation of the peak flow was always able to be recognized. It seemed that the state of the airway varied during the panting method. The Raw measured during 0.5 Hz breathing (nearly quiet breathing) had small variability. Because the airway state during 0.5 Hz breathing was nearly the same as that during quiet breathing, measurement of Raw (0.5Hz) can be regarded as a practical method in patients with PE.

Aged↗
PubMed1980

[Studies on hypercapnia in patients with lung tuberculosis (author's transl)].

Pathophysiologic ecologic and therapeutic study was made on respiratory disturbances, especially on hypercapnia in patients with lung tuberculosis. 1) Of all in-patients (497 cases), 192 (38.6%) had respiratory disturbances, among which 70 cases (14.1%) exhibited hypercapnia. 2) Of these hypercapnic patients, about one-third (31.4%) were after thoracoplastic surgery, the main disturbances being restrictive in nature. In the half of non-operative cases, obstruction and inadequate gas mixing were the main cause for hypercapnia. 3) Critical values for inducing hypercapnia were % VC 45 for patients with restrictive disturbances and FEV1-0%/expected VC 40 for hypercapnic patients. 4) Significant band in the PaCO2 similar to (HCO-3) regression chart in patients (20 cases) with chronic stable hypercapnia showed a linear relationship with an increasing PaCO2, given by an equation, (HCO-3)p = 7.7 + 0.43 PaCO2 (PaCO2 45 -- 113 mmHg, SD = +/- 1.2, r = 0.99). Twelve percent of the unstable patients (100 cases) showed an alkalosis (pH greater than 7.45) over the range above 45 mmHg of PaCO2. 5) Even in patients with normal pH values, administered HCO-3 was estimated to move into the intracellular or interstitial fluid. 6) Increase in oxygen consumption was greater with increasing ventilation volume in hypercapneic patients. Even in these patients, voluntary or drug-induced hyperventilation caused a decrease in PaCO2, resulting in an amelioration of suppressed respiration under oxygen or even pethidine HCl administration. Discussion was made on the usefulness of these therapies on patients with hypercapnia.

Blood Gas Analysis↗
PubMed1976

Capillaries in the subarachnoid space.

The fine structure of the small vessels of the subarachnoid spaces in the rat and mouse cerebral and cerebellar cortices was examined. Small vessels with lumen under 7 mu and whose walls consisted of a single layer of endothelial cells were found. These vessels are regarded as true capillaries.

Animals↗