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T Oohashi

Publications and source records attributed to T Oohashi.

42 records · Page 3Linked to original sources
PubMed1992

Correlation of serum concentration of alpha 1-acid glycoprotein with lymphocyte blastogenesis and development of experimentally induced or naturally acquired hepatic abscesses in cattle.

Changes in serum alpha 1-acid glycoprotein (alpha 1AG) concentration in cattle with hepatic abscesses were observed, and function of alpha 1AG was evaluated, particularly its influence on cellular immune response. Test cattle (n = 4) were inoculated with Fusobacterium necrophorum, control cattle (n = 2) were inoculated with inactivated bacteria, and naturally affected cattle (n = 11) were found in a slaughterhouse. Determination of alpha 1AG was made by use of a single radial immunodiffusion method. The action on lymphocyte blastogenesis was determined by [3H]thymidine incorporation. Cultured lymphocytes from healthy cattle were treated with variable concentrations of alpha 1AG purified from serum obtained from cattle with hepatic abscesses and suppression of blastogenesis stimulated by each of 3 mitogens was measured. In cattle with experimentally induced abscesses, serum alpha 1AG concentration increased for 7 to 10 days after F necrophorum inoculation, its change being parallel to that of sialic acid. High concentration of alpha 1AG was found in naturally affected cattle and was highly correlated to sialic acid concentration. Suppression of lymphocyte blastogenesis in cattle with experimentally induced hepatic abscesses was highly correlated to serum alpha 1-AG concentration.

Animals↗
PubMed1990

[A case of intrasellar and suprasellar meningioma with hypopituitarism].

A case of intrasellar and suprasellar meningioma with hypopituitarism is reported. A-64-year-old woman was admitted to our hospital with chief complaints of reduced consciousness and inactivity. She had a history of subarachnoid hemorrhage 20 years previously, and developed right third nerve palsy. Physical examination demonstrated that, in consciousness, she was stuporous, and she had impaired visual acuity and palsy in the right third nerve. An X-ray film of the sella turcica showed enlargement and intrasellar calcification. A CT scan with contrast enhancement revealed a homogenously enhanced mass in the sella and suprasellar region. A cerebral angiogram showed elevation of the bilateral A1 portion of the anterior cerebral artery. No tumor blush was evident. Endocrinologic function tests confirmed impaired anterior lobe hormones and hypothyroidism. Preoperative diagnosis was pituitary adenoma. The tumor was subtotally removed by using the transsphenoidal approach and right frontotemporal craniotomy was carried out using microsurgery in a two staged operation. The tumor was yellowish-grey, partly firm in consistency, and it had a soft elasticity. Operative findings showed that the dura matter of the tuberculum sella, the anterior and posterior clinoid process, the medial sphenoidal ridge, and the wall of the cavernous sinus were intact, which was confirmed at autopsy, later. Microscopical examination revealed a mixed meningothelial and fibroblastic meningioma with papillary component and psammomatous bodies. The tumor was thought to originate in the diaphragma sella, and to extend in intrasellar and suprasellar directions. The patient died of basilar artery thrombosis. In clinical and radiological examination, there is no definite difference between pituitary adenoma and intrasellar meningioma.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenoma↗
PubMed1989

[A scirrhous carcinoma of the nipple suspected of being Paget's disease].

Discussed is a 38-year-old woman, whose chief complaints were an eczema-like lesion and itching of the nipple in the left breast. Thus, Paget's disease was suspected, and touch cytology and a cytological biopsy of an aspirated specimen were done. The results indicated a class II and class V status, respectively. A radical mastectomy, therefore, was performed immediately. Macroscopic findings of the resected tissue showed no tumor in the nipple or in the mammary gland. A histological examination led to the determination of a scirrhous carcinoma of the nipple. Seventeen months after the operation, the patient has had no recurrence.

Adenocarcinoma, Scirrhous↗