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Biomedical subjects

T Owman

Publications and source records attributed to T Owman.

At least 37 records · Page 2Linked to original sources
PubMed1980

A large-bore teflon endoprosthesis with side holes for nonoperative decompression of the biliary tract in malignant obstructive jaundice.

A large-bore Teflon tube with side holes was used for nonsurgical palliative bile drainage in eight patients with malignant tumors. The drainage period ranged from 5 to 26 weeks. The bile drainage through the endoprosthesis was regarded as optimal in two patients, satisfactory in four, and ineffective in two. Significant complications of the method are intervening bile duct infections, risk of sepsis, spontaneous dislodgement, and occlusion of the endoprosthesis.

Adult↗
PubMed1980

Complications of percutaneous transhepatic catheterization of the portal vein and its tributaries.

The complications of percutaneous transhepatic catheterization of the portal vein and its tributaries were assessed in 406 patients in whom 440 examinations had been performed and 8 unsuccessful attempts. Clinically relevant complications consisting of abdominal or external hemorrhage occurred in 24 cases with fatal outcome in 3. Complications involving the right pleural space occurred in 13 patients: collection of ascitic fluid in 6, bile effusion in 5 and bleeding in 2. Laparotomy was needed in 7 cases due to intraabdominal hemorrhage. The gallbladder was unintentionally punctured in 4 cases. Furthermore, a variety of minor complications of little clinical significance, such as extravasation of contrast medium, subintimal injection of contrast medium and minor intrahepatic hematomas, were observed.

Adolescent↗
PubMed1980

Estimation of renal pelvic volume in free urinary flow and in ureteral stasis. An experimental study in the rabbit.

At urography the radiopacity of the pelvis increases with the product of iodine concentration of the urine and its layer thickness. The layer thickness is proportional to the third root of the volume. Using this knowledge, we estimated the volume of the renal pelvis in rabbits and found it to be proportional to the diuresis up to a level of approximately 0.8 ml per min, after which a maximal dilatation seemed to be reached. By this means, the estimated density of the renal pelvis can be calculated. This model of evaluating urographic contrast agents is thought to be more appropriate than and complementary to the mere determination of urinary iodine concentration.

Animals↗
PubMed1979

Infusion tomography and ultrasonography of the gallbladder in the diagnosis of acute cholecystitis.

Sixty-three patients with the clinical suspicion of acute cholecystitis were examined with infusion tomography of the gallbladder. Ultrasonography was performed in 51 of these cases. The technique and diagnostic principles of both methods when used in combination is stressed. Thus in a case of gangrenous cholecystitis when opacification of the gallbladder wall may not appear at infusion tomography, ultrasonography may demonstrate signs of gallbladder disease. Infusion tomography, on the other hand, may be of great value if ultrasonography is not informative.

Acute Disease↗
PubMed1979

Heparinized catheters for long-term intraarterial infusion of 5-fluorouracil in liver metastases.

A heparinized catheter was used for the regional infusion of 5-fluorouracil in seven patients with liver metastases. The hepatic artery was catheterized from the left brachial artery. The period of treatment varied from one to 13 weeks. Pull-out angiograms, obtained after eight catheterizations, revealed complete occlusion of the brachial artery in five and partial occlusion in three, although no patient had ischemic symptoms in the hand. Thus, heparinization of the catheter did not prevent thrombosis during long-term infusion therapy.

Aged↗
PubMed1979

Intraarterial infusion chemotherapy (5-fluorouracil) in patients with inextirpable or locally recurrent rectal cancer.

A retrospective analysis of the results of treatment of advanced rectal cancer of the pelvis with regional intraarterial infusion of 5-fluorouracil (5-FU) is reported. A special technic for positioning the catheters selectively in the internal iliac arteries justifies this analysis. Four patients with primary inextirpable rectal cancer and 10 patients with locally recurrent rectal cancer have been treated. No immediate mortality was noted. Relief of pain was noted in two-thirds of the patients. An objective tumor response was noted in three patients with locally recurrent disease. In one patient with primary inoperable cancer it was possible to extirpate the tumor after infusion therapy. An improvement in quality of life during the first 2 months after therapy was achieved in half of the patients as judged by their performance. Complications were not serious. Hematomas with infection were seen in one patient, two patients had septicemia, and three patients had transient oliguria. Transient thrombocytopenia was reported in two patients. The results indicate that infusion therapy produces a reasonable response such as palliation of pain. Only minor complications were seen and easily controlled. The advantages of infusion therapy are that it can be given in a reasonable time with only a short hospital stay.

Adult↗
PubMed1979

Comparison of monomer, dimer and non-ionized medium at urography with simulated compression; an experimental study in the rabbit [author's transl].

Density, estimated through renal pelvic volume as calculated according to previous experiments (Owman 1978) and urinary iodine concentration, is suggested to be more accurate than, and complementary to, mere determination of urine iodine concentration and diuresis when evaluating and comparing urographic contrast media experimentally. More reliable dose optima are probably found when calculating density rather than determining urine concentrations. Of the examined media in this investigation, metrizamide and P 268 are by far superior, giving higher density, higher urinary concentrations, and metrizamide also less diuresis.

Animals↗
PubMed1979

Obliteration of esophageal varices by PTP: a follow-up of 43 patients.

The percutaneous transhepatic portal vein catheterization (PTP) with selective obliteration of the coronary vein and/or the short gastric veins in treating bleeding esophageal varices was introduced in 1974. In order to prevent recanalization of the vessels Bucrylate (isobutyl-2-cyano-acrylate) has been used in 43 patients 55 times during a period of 34 months (October 1975 to July 1978). The obliterative treatment was followed by rebleeding in 35% of the cases and continued bleeding occurred in two patients. Fourteen patients were treated on 16 occasions during acute bleedings, and five of these (36%) died within two months from a portal vein thrombosis caused by the obliterative procedure. Because of these findings PTP with obliteration of the veins feeding the esophageal varices is not recommended as an elective way of treatment. It should only be used in the acute bleeding patient when transesophageal sclerosering therapy, continuous vasopressin infusion and balloon tamponade have failed. Fifty-six per cent of the patients acutely treated stopped bleeding for more than one week, thus avoiding an emergency shunt or devascularization operation which are associated with a high mortality rate.

Adolescent↗
PubMed1979

[Percutaneous transhepatic procedures for diagnosis and therapy in obstructive jaundice (author's transl)].

The techniques of percutaneous transhepatic cholangiography, intubation of the bile ducts for external and internal drainage, application of endoprostheses and removal of biliary tract stones as performed at the Department of Diagnostic Radiology in Lund, Sweden, are described. A flow diagram for diagnostic and therapeutic procedures in patients with obstructive jaundice is discussed.

Adenoma, Bile Duct↗
PubMed1978

Isobutyl 2-cyanoacrylate (bucrylate) in obliteration of gastric coronary vein and esophageal varices.

Percutaneous transhepatic portography was performed in 22 patients with liver cirrhosis and portal hypertension. All patients had bled or were bleeding from presumed esophageal varices. One or more veins feeding esophageal varices were occluded with bucrylate. Follow-up examination in eight patients 1-12 months later showed recanalization of previously obliterated veins in six; however, these veins were markedly smaller than before the procedure. In patients where veins were still occluded, new veins had opened up and carried blood to the esophageal varices, which were filled to a lesser degree than before. In our experience, bucrylate is superior to Gelfoam, thrombin, and Etolein in producing venous occlusion.

Adult↗
PubMed1977

The diagnosis of the small resectable pancreatic carcinoma.

ERCP and angiography are essential for the accurate diagnosis of pancreatic carcinoma. ERCP is of value in detecting a pancreatic tumour and is the only examination which makes it possible to detect a small pancreatic carcinoma. Angiography is indispensable for the evaluation of the extent and size of the carcinoma, for prediction of resectability, and for differentiation between pancreatitis and carcinoma. Thirty-one out of 32 pancreatic carcinomas (96%) were correctly diagnosed pre-operatively by the use of a combination of the two examinations. Ten of them (31%) were resectable, and of these six measured less than 2 cm in diameter.

Aged↗
PubMed1977

Blood flow in renal carcinomas evaluated by a dye dilution technique and angiography.

In 31 patients with renal carcinoma referred for angiography, rapid sequence angiography was performed in 25. In 18 of the patients determination of renal blood flow and related parameters was made in conjunction with the angiography. Carcinomas with high and medium-high differentiation comprised Group I, while those with medium and poor differentiation constituted Group II. In both groups a positive correlation was demonstrated between the renal blood flow and the tumour area. In group I, positive correlation (t greater than 2) was demonstrated between the vascular volume and the tumour area, between the vascular resistance and the emptying time of the tumour arteries and the normal renal arteries. There was some degree of shunting of blood in all tumours. Comparison of the arterial emptying time of the tumour arteries with the parenchymal arteries does not allow of staging of renal carcinomas. The degree of shunting may be an indication of the degree of malignancy and poor differentiation.

Dye Dilution Technique↗