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Biomedical subjects

T P Joseph

Publications and source records attributed to T P Joseph.

At least 19 recordsLinked to original sources
PubMed2002

Autosomal recessive limb girdle myasthenia in two sisters.

Limb girdle myasthenic syndromes are rare genetic disorders described under the broad heterogeneous group known as congenital myasthenic syndromes and present with mixed features of myasthenia and myopathy. The familial limb girdle myasthenia has been described as one with selective weakness of pectoral and pelvic girdles, showing a positive response to edrophonium chloride. A report of two sisters affected by this disorder is presented.

Adolescent↗
PubMed2001

Hemispherotomy for paediatric hemispheric epilepsy.

We present here the results of our series of peri-insular hemispherotomy for intractable hemispheric epilepsy. There were 6 children in this series with a mean age of 10.2 years and mean duration of seizures of 7.2 years. The seizure results were excellent in all children and they also showed significant improvement in functional status. This procedure has significant advantages when compared to other forms of hemispherectomy. However, a larger experience with longer periods of follow-up is needed.

Adolescent↗
PubMed1993

Rotatory seizures of frontal lobe origin.

We report a patient with true rotatory seizures. The CT scan showed a right frontal calcified lesion and the EEG showed focal epileptiform discharges over the right frontal region. The seizures responded well to phenytoin therapy.

Adult↗
PubMed1989

Acute intestinal obstruction.

Nine hundred and four children with intestinal obstruction were studied. Necrotising enteritis was the commonest cause of intestinal obstruction in children. Acute intussusception was the second commonest cause in the whole group and the commonest cause in children under 1 year of age. Less common causes included band obstruction, sub acute intestinal obstruction and remnants of vitello-intestinal duct. A steady and significant improvement in the results of treatment was noted in children suffering from necrotising enteritis in the study period.

Child↗
PubMed1977

The non-operative management of splenic trauma.

Non-operative management of splenic trauma is not a widely accepted method of treatment. During the period 1964 to 1976, 39 children were treated in the Adelaide Children's Hospital for splenic trauma. Twenty-four were managed without operation, while 15 were treated by splenectomy. Recently, splenic scan has helped in the diagnosis and management of splenic injuries. From our observations, it appears that non-operative treatment of a proven splenic injury is safe and the ideal initial treatment in the paediatric age group, when the spleen is the only intraabdominal organ injured, and the vital signs are stable with the application of adequate resuscitative measures.

Blood Transfusion↗
PubMed1975

Nasotracheal intubation in diphtheria.

Nasotracheal intubation can be used effectively for the relief of upper airway obstruction in diphtheria. It has many advantages over tracheostomy; it avoids an operation and it eases anxiety of the parents. Of 57 patients so treated, 50 recovered without injury to the larynx in any patient.

Airway Obstruction↗
PubMedDate not supplied

Temporofacial zygomycosis in a pregnant woman.

A 38-year-old Omani woman, seven months pregnant, developed extensive zygomycosis involving maxillary and temporal bones. No evidence of any underlying immune deficiency was detected except that which may be attributed to pregnancy. After delivery the patient was treated with repeated courses of amphotericin B, which resulted in a complete clinical resolution. Zygomycosis in uncomplicated pregnancy has not been previously described.

Adult↗