Biomedical subjects
Publications and source records attributed to T P Shopper.
Serum chemistry is becoming more complex as newer and more sophisticated diagnostic machinery is used by an increasing number of health care centers. Many automated clinical analyzers can test for more than 20 substances from a small sample of serum. The dentist, as part of the health care team, must keep informed of current developments.
Testing for three serum markers in screening for hepatitis B disclosed 34 of 292 patients testing positive to anti-HBc. Responses to the medical history alone disclosed only one patient with a history of hepatitis. Seroanalysis, plus a complete history, yields the most reliable results.
Two hundred eighteen professional students were surveyed to uncover any association of recurrent aphthous stomatitis (RAS) with a history of allergic diathesis. No significant relationship was uncovered. From this population approximately equal numbers of RAS-positive and RAS-negative subjects were challenged with suspected foodstuff agents thought to have a potential causative role in occurrence of the disease. The results failed to document any causative effect with regard to tomatoes, strawberries, or walnuts.
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PURPOSE: The primary objective of this study was to determine the most commonly biopsied gingival lesions in a university-based school of dentistry biopsy service. METHODS: The biopsy service at the Louisiana State University Medical Center School of Dentistry accumulated 30,056 cases during a 24-year period (1969 to 1992). Microcomputer technology was used to sort these cases to study the gingival lesions including the incidence of neoplasm and epidemiologic factors of age, gender, and race. RESULTS: Of the 30,056 biopsies submitted for diagnosis, 3,859 (12.8%) were taken from the gingiva. The most common diagnoses for gingival lesions were periodontal disease, fibrous hyperplasia, pyogenic granuloma, peripheral ossifying fibroma, and epithelial hyperplasias/hyperkeratoses. Benign and malignant neoplasms made up 15.5% of the cases. The largest number of cases was from individuals between the ages of 30 and 39 (18.2%). Of the biopsies submitted, 63.3% were from female patients, and 85.8% of the cases were from Caucasian patients. CONCLUSION: Gingival lesions often are detected by dental hygiene and dental professionals. Knowledge of the frequency and presentation of the most common gingival lesions is beneficial in developing a clinical impression of such lesions encountered in practice.