[Oncogenic virus RNA-HTLV (human T-cell leukemia-lymphoma virus)].
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Deltaretrovirus↗
Biomedical subjects
T Paszkowski
Publications and source records attributed to T Paszkowski.
Kynurenine aminotransferase I activity in human placenta.
The aim of the study was to detect and characterize placental kynurenine aminotransferase I (KAT I) activity in physiological pregnancy at term. Placental KAT I was inhibited by l -glutamine, l -tryptophan, and l -phenylalanine and reached optimum activity at pH 9.8. When pyruvate was used as a co-factor, the KAT I activity was significantly higher than the activity of this enzyme in the presence of 2-oxoglutarate. In the light of our findings placental KAT I seems to have biochemical characteristics of KAT I detected in human brain.
Enzyme Inhibitors↗
[Content of essential metals in colostrum of women delivered by cesarean section in early puerperium].
The concentrations of magnesium, iron, copper and zinc were determined by atomic absorption spectrometry in the colostrum of 5 women in puerperium after delivery by Cesarean section. The samples of colostrum were obtained for examination between 11 and 12 hours on puerperium days from 4th to 7th. A significant rise of the concentration between these days was noted only in the case of iron (p less than 0.05). The differences in the levels of other metals over time period were random. The daily supply of these elements with milk to the breast-fed newborn increased evidently in that time period. Statistically significant differences were noted between days 4 and 6 (p less than 0.05) and the successive days (p less than 0.01). The daily supply of magnesium estimated on the 8th day of puerperium was not exceeding 50% of the lower limit of the recommended daily supply of this metal for newborns and infants. The contents of iron and copper in the daily portion of colostrum were at the borderline of the recommended values, and only in the case of zinc they fell within the range of these values.
Cesarean Section↗
[Contamination of human milk with nitrates and nitrites].
Human milk nitrates and nitrites were assayed colorimetrically. Colostrum samples were collected on the 3rd postpartum day from 59 women inhabiting Puławy region and being potentially exposed to nitrogen compounds emitted from the industrial sources. Thirty five Lublin inhabitants serving as a control group were matched in age, parity and duration of pregnancy. Geometric mean value of nitrates and nitrites concentration in the human milk being 2.83 mg/L and 0.46 mg/L, respectively were higher in the examined group than those in the control group /2.76 mg/L and 0.32 mg/L/ but difference was statistically insignificant. Ratio of nitrates and nitrites in the examined samples was 7.38 on the average and the concentration of those compounds was related statistically significantly /p less than 0.001/. The average daily intake of nitrates and nitrites by the breast-fed neonates was 0.12 mg/kg body weight and 0.02 mg/kg body weight, respectively. These values did not exceed corresponding ADI recommended by the Joint Expert Committee of FAO/WHO in none case. Significantly positive correlation of examined mothers' age and parity with nitrates content in their colostrum was seen. In view of the obtained results is may be assumed that the examined colostrum samples contain low amounts of both nitrates and nitrites.
Breast Feeding↗
The associations between serum alpha-1-antitrypsin level and the whole blood contents of trace metals in normal women in reproductive age.
The concentration of Alpha-1-Antitrypsin (A-1-AT) in the blood serum was measured by single radial immunodiffusion in 21 healthy women in reproductive age. Simultaneously the whole blood levels of cadmium, lead, copper and zinc were determined by atomic absorption spectrometry. Serum A-1-AT correlated significantly with blood copper (r = 0.55, p less than 0.01). The importance of quantitative relations between "acute phase reactants" in blood serum and the blood trace metals is discussed from the point of view of reproductive medicine.
Adult↗