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T Picton

Publications and source records attributed to T Picton.

10 recordsLinked to original sources

Human auditory evoked potentials to frequency-modulated tones.

Three experiments evaluated steady state and transient auditory evoked potentials (EPs) to tones that were sinusoidally modulated in frequency and to tones that alternated between two frequencies with a linear ramp. The steady state responses to sinusoidal FM were small and difficult to record at both the first and second harmonics. Ramp FM evoked larger and more consistent second harmonic steady state responses than the sinusoidal FM. Only the ramp FM stimuli elicited transient EPs and these only at low modulation rates. These responses were larger to upward ramps than to downward ramps. The response to two simultaneously presented ramp FM tones differed from the sum of responses to the individual tones, indicating some interaction in the processing of the two stimuli.

Acoustic Stimulation↗

Reaction time after head injury: fatigue, divided and focused attention, and consistency of performance.

Three groups of patients who had suffered head injury were compared with matched control subjects on reaction time (RT) tasks. Group I consisted of outpatients previously hospitalised for head injury of wide ranging degrees of severity, assessed at varying intervals after injury. Group II was composed of non-hospitalised mildly concussed patients. Group III was made up of head injured patients of varying degrees of severity assessed 7-10 months after initial hospitalisation for their injury. The reaction time tests were graded in difficulty, from a simple RT response to a complex choice RT test. In addition, subjects were compared in their ability to ignore redundant information during one of the choice RT tests. The findings indicate that traumatic brain injury causes slower information processing, deficits in divided attention, an impairment of focused attention, and inconsistency of performance.

Adolescent↗

Human auditory steady state responses: effects of intensity and frequency.

Human auditory steady state responses were recorded in 41 normal subjects and 22 patients with hearing loss. The effect of intensity on the responses at different tonal frequencies was assessed using the sweep technique. The amplitude of the responses increases and the phase delay decreases with increasing intensity. Both the amplitude and the phase delay are smaller for high frequency tone bursts. Notched noise decreases the amplitude of the response by a factor of two but does not affect the phase of the responses. Thresholds were estimated in waking subjects using two techniques: intensity sweeps analyzed by linear regressions, and fixed intensities analyzed by Hotelling's T2 test. Frequency-specific thresholds obtained with notched noise were less variable and more accurate with the fixed intensity technique. In patients with sensorineural hearing loss the amplitude increased more with increasing intensity above threshold than in patients with conductive hearing loss.

Adult↗

Evaluation of brain-stem auditory evoked potentials using dynamic time warping.

Dynamic time warping is a procedure whereby portions of a temporal sequence of values are stretched or shrunk to make it similar to another sequence. This procedure can be used to align the brain-stem auditory evoked potentials recorded from different subjects prior to averaging. The resultant warp-average more closely resembles the wave form of a typical subject than the conventional average. Dynamic time warping can also be used to compare one brain-stem auditory evoked potential to another. This comparison can show the differences that result from changes in a stimulus parameter such as intensity or repetition rate. When a patient's wave form is compared to a normal template, warping can identify the peaks in the patient's wave form that correspond most closely to the peaks in the normal template. Compared to an experienced human interpreter, warping is very accurate in identifying the waves of normal brain-stem auditory evoked potentials (error rate between 0 and 4%) and reasonably accurate in identifying the peaks in abnormal wave forms (error rate between 3 and 18%).

Adult↗

Interweaving and overlapping of evoked potentials.

The refractory effect of one stimulus upon the response to a closely following stimulus in a different modality is much less than upon the response to a stimulus in the same modality. It is therefore far more efficient to record responses to stimuli in different modalities concurrently than to record each one separately. We evaluated 2 techniques for concurrent recording. Interweaving involves recording the response to one stimulus in the intervals between recording responses to other stimuli. Overlapping occurs when two or more responses are at times being simultaneously recorded. Interweaving and overlapping reduced the time required to record auditory brain-stem responses, short-latency somatosensory evoked potentials and pattern-reversal visual evoked potentials by a factor of 3 over the time required to record each response separately. Overlapping caused no significant change in the evoked potentials. Depending upon the actual timing schedule, interweaving may distort the evoked potentials if later parts of the response to one stimulus override the evoked potential to a following stimulus. Filtering and randomization of stimulus timing may attenuate the effects of these overriding potentials.

Adult↗

The Crib-O-Gram in the NICU: an evaluation based on brain stem electric response audiometry.

This study evaluated the Crib-O-Gram as a screening test for hearing loss in NICU infants using Brain Stem Electric Response Audiometry (BERA) as the standard. Two Crib-O-Gram tests were administered to 280 babies within 48 hours of BERA testing. An additional 26 babies received BERA and one Crib-O-Gram test. Correlation coefficients for the two Crib-O-Gram scalar scores were calculated separately for a group of preterm (31 to 37 weeks) and a group of full term and older (38 to 54 weeks) infants, with values of 0.36 and 0.52, respectively. This indicates that the Crib-O-Gram has poor reliability for a screening test, particularly for preterm babies. Approximately one-third of babies with normal BERA thresholds failed Crib-O-Gram screening. The identification of hearing loss by Crib-O-Gram increased with the severity of the loss. Crib-O-Gram was able to identify moderately severe hearing losses in full term and older babies.

Acoustic Stimulation↗