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Biomedical subjects

T Poch

Publications and source records attributed to T Poch.

10 recordsLinked to original sources
PubMed1992

[The clinical picture of Fuch's heterochromic cyclitis].

The authors are presenting their experience with the diagnosis and treatment of Fuchs' heterochromic cyclitis. They followed-up 13 patients with this disease for 0.5-3 years. Most often the patients were sent to the clinic with the diagnosis of recurrent anterior uveitis not responding to the treatment with corticosteroids and mydriatics. Patients underwent numerous investigations including neurological, internal and rheumatological examinations. Antibodies against EBV, HSV and CMV were detected. The examination of humoral immunity and HLA was done. The authors describe the ophthalmological findings, the course of the disease and the treatment. They did not find any correlation in the laboratory investigations and the course of the disease, the diagnosis is based on the clinical picture. They point out the advantage of the small incision in the extracapsular extraction of cataract in these patients.

Adult↗
PubMed1992

[Diagnostic problems in uveitis].

The authors examined and followed up for two years 102 subjects who were referred to the First Ophthalmological Clinic of the First Medical Faculty, Charles University, Prague on account of idiopathic uveitis. They used a wide range of examination methods by means of which they were able to differentiate idiopathic uveitis from anterior uveitis with the presence of HLA B27, Fuchs disease and Eales disease. A quarter of the patients suffered from general disease, internal or neurological, where uveitis can be one of the symptoms. This disease was not diagnosed at the time of exacerbation of uveitis. The authors describe a series of examination methods and their contribution to the assessment of the correct diagnosis. They discuss the development of views regarding the diagnosis of idiopathic uveitis and views on the treatment of this disease.

Adult↗
PubMed1992

[Autoimmune etiology of endogenous uveitis].

The authors presents a review of some findings on the basis of which it is possible to classify uveitis, retinitis and choroiditis already at the time of its onset, and in particular subsequently, as an autoimmune disease. They consider this review an adequate basis for immunosuppression therapy of uveitis at the very onset, although they do not analyze it in the submitted paper.

Autoimmune Diseases↗
PubMed1977

Peroxidase and pseudoperoxidase reactions in relation to sudanophilia.

A selective staining of hemoglobin in erythroid cell series was achieved by use of Sudan Black B (modified method of Sheehan and Storey) if optimal amount of hydrogen peroxide was added to the staining mixture. The effect of some inhibitory agents (KCN, wet heat, pH) on this staining as well as on the Lepehne's pseudoperoxidase reaction for hemoglobin was similar. Both reactions were more resistant to these factors than the peroxidase reactions and sudanophilia in granulocytes in which both could be blocked by the pretreatment with absolute methanol. Moreover the effect of some extraction procedures for lipids on both myeloperoxidase reactions and sudanophilia was investigated. The results support the view that the sudanophilia in granulocytes is due to their peroxidase activity and for the staining of hemoglobin by use of Sudan Black B with H2O2 its pseudoperoxidase activity is responsible. In addition the effect of the substitution of phenolphosphate by dihydroxybenzenes on granulocyte sudanophilia is reported.

Cyanides↗
PubMed1975

Phagocytic activity of leukaemic blasts.

Phagocytic activity of leukaemic blasts in 20 adults and 16 children suffering from acute leukaemia was studied in vitro by the use of ferrioxidsaccharate. Most frequently phagocytosing blasts were encountered in myelomonocytic leukaemias. The morphological character of positive blasts resembled often that of monocytoid cells. In lymphoblastic and reticular leukaemias phagocytic ability of blasts was an exceptional finding.

Acute Disease↗
PubMed1975

[Problems of cytochemistry of leukocytes].

In investigating the atypical granula in myeloic cells cytochemically the positivity of DMAB reaction identifies the specific eosinophilic nature of these granula. The slightly modified methods of representing histones allow those histones which are rich of lysine and arginine to be differentiated. With their help those differences can be grasped which exist between the condensed chromatin of lymphocytes and the mature neutrophils caused by the presence of histones being rich of lysine and arginine. New possibilities of examining the proteins in leukocytes in a cytochemical way as well as in blood- and bone-marrow cells are provided by colouring with palatine fast black, the use of which also points to certain differences in the chromatin of lymphocytes and neutrophils.

Cell Nucleus↗