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T Ponge

Publications and source records attributed to T Ponge.

At least 37 records · Page 2Linked to original sources
PubMed1988

The efficacy of selective unilateral temporal artery biopsy versus bilateral biopsies for diagnosis of giant cell arteritis.

Two hundred bilateral temporal artery biopsies performed prospectively in 200 patients suspected of having giant cell arteritis (GCA) were always preceded by Doppler flow study and local clinical examination. If bilateral temporal artery biopsies had been guided by positive local clinical examination, 24 positive biopsies would have been found, and Doppler studies would have improved the diagnostic score to 39; however, the biopsies gave 42 histologically positive results, providing the best diagnostic yield. The possibility of GCA with normal Doppler flow studies was noted as well as the existence of relatively asymptomatic forms of GCA, so that systematic performance of bilateral temporal artery biopsy would seem justified in any case of suspected GCA.

Aged↗
PubMed1987

[Primary Gougerot-Sjögren syndrome with necrotizing polymyositis: favorable effect of hydroxychloroquine].

A 61-year-old woman was admitted for acute arthralgias and proximal weakness in all four limbs. Clinical examination found xerostomia, xerophthalmia, enlarged parotid glands. The Schirmer test was positive and the salivary gland biopsy showed a mononuclear, lymphoid, sometimes nodular infiltrate. A muscle biopsy showed necrotizing myopathy with perifascicular atrophy. The patient refused steroids and was given hydroxychloroquine (600 mg daily). She improved gradually, and one year later there were no further complications. The favorable course both of Sjögren's syndrome and polymyositis with hydroxychloroquine treatment is unexpected. This led us to suppose that both could have had a common cause.

Female↗
PubMed1985

[Clavicle osteolysis in MacDuffie's syndrome].

MacDuffie's syndrome emerges from systemic vasculitis as including recurrent urticaria-like skin lesions, episodic angio-oedemas, articular manifestations and abdominal pains, with a tendency to affect women. Renal involvement may burden the prognosis. Hypocomplementemia is usual by deficiency of the classical pathway. Corticosteroid therapy is habitual. The case reported, fitting to this nosological entity offers two new features: in the first place, the osteolysis of the distal part of the clavicle whereas the joints are not affected by destroying lesions; then the non steroidal anti-inflammatory drugs was effective within a period of one year without complication.

Adult↗
PubMed1984

[Thalamic hematoma: review of semiology and computed x-ray tomography in 14 cases].

Thalamic hematomas occur chiefly in hypertensive patients aged 50 to 70; characteristic presentation is a triad associating a sensory syndrome, oculomotor disorders, and alterations in consciousness; computed tomography not only establishes diagnosis but provides additional information, particularly on the size and volume effect of the hematoma which may, according to some authors, indicate surgical removal.

Adult↗
PubMed1983

[Spontaneous primary hematomas of the cerebellum].

Spontaneous cerebellar hematoma is a well-defined radio-clinical entity. It may occur, not only in patients with risk factors (hypertension for instance), but also in those who have no specific etiologic factors. Onset is usually sudden. The characteristic clinical triad consists of alterations in consciousness, peripheral facial palsy and various oculomotor disorders. Poor prognosis factors related to the size and localization of the hematoma can be determined by computed tomography. We believe that surgery is indispensable in hydrocephalus as well as in increasing or secondary onset of alterations in consciousness.

Adult↗
PubMedDate not supplied

[Paraneoplastic dermatopolymyositis].

In a retrospective study covering 11 years, 59 adult cases of dermatomyositis or polymyositis were reviewed. The disease was of paraneoplastic origin in 9 cases (15,25 p. 100), the same proportion as that found in the literature (14,6 p.100). The striking female predominance (8/9 cases) and the patients' mean age (61.11 years) were higher than those noted in non-paraneoplastic dermato- and polymyositis in adults (female predominance 34/50, mean age 52.9 years). Clinically, out of 9 patients 7 had dermatomyositis and 2 had polymyositis. The disease was discovered at the same time as the neoplasia in 7 of the 9 cases. Muscle histology showed that in contrast with non-paraneoplastic cases of dermatomyositis-polymyositis those of paraneoplastic origin had moderate lesions without fibrosis.

Aged↗
PubMedDate not supplied

Giant cell arteritis presenting with aortic dissection: two cases and review of the literature.

Aortitis is the most serious location of the disease giant cell (temporal) arteritis (GCA). Aortic dissection or the rupture of an aortic aneurysm can be responsible for sudden death among patients with GCA. This report discusses two cases of GCA presenting with aortic dissection. One case had histologically proven giant cell aortitis. The second case was a fatal aortic dissection preceded by a stroke. We describe the main features of aortic dissection and aortitis during GCA, reviewing the existing literature on this subject, and focusing on the requirement of prospective aortic imaging studies to screen patients with this kind of location.

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PubMedDate not supplied

[Limitations of normal eosinophilia or possible influence of nonsteroidal anti-inflammatory agents].

Statistical analysis of eosinophilia of 331 patients at the onset of hospitalisation define a logarithmic standard population of 327 patients whose eosinophilia rates stand between 0 and 810/mm3, among them 24 lies between 500 and 810, and 4 whose eosinophilia rise over 1,000/mm3. These 4 patients had transient hypereosinophilia whose etiology was defined only in 2 cases. The 24 patients with eosinophilia between 500 and 810/mm3 were significantly more frequently men, with rheumatoid disease (specially sciatica) and users of non steroidal antiinflammatory drugs (NSAID) than the general population. It suggest that NSAID may rise eosinophilia rates inside normal limits.

Adult↗
PubMedDate not supplied

[Evaluation of drug consumption by hospitalized patients. Prospective survey].

Drug use was assessed in a prospective 6-month study carried out in the Department of General Medicine V and Rheumatology of the Nantes Regional Hospital Center. An attempt was made to evaluate consumption as realistically as possible, and a judgment was made based on the consensus of the medical team as to whether the prescription was justified or not. The mean number of drugs consumed by each patient was 2.8; 60% being prescribed for cardiovascular and neuropsychiatric purposes. As 33% of the prescriptions were considered unnecessary, it would appear that use was excessive in these hospitalized patients.

Aged↗
PubMedDate not supplied

[Iatrogenic disease. Prospective study, relation to drug consumption].

The role of drug use in iatrogenic pathology was studied prospectively in a hospital department. It wa s found that patients received an average of 2.8 drugs and that 30% of the prescriptions were unnecessary. During this six-month study of all patients admitted to a general medicine and rheumatology department, there were 67 iatrogenic accidents affecting 12.3% of the population: 41.8% of the accidents were directly responsible for hospitalization, 35.4% were due to therapy initiated during hospitalization and 32.8% occurred during the hospital stay but were the result of earlier treatment. Moreover, 26% of the accidents were related to what was considered to be unnecessary therapeutics. This study shows that elevated iatrogenic pathology was due to excessive drug use. However, the degree of severity of the adverse effects varied considerably, and some could have been easily avoided.

Aged↗