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Biomedical subjects

T R Kapur

Publications and source records attributed to T R Kapur.

18 recordsLinked to original sources
PubMed1995

Causes of failure of combined approach tympanoplasty in the treatment of acquired cholesteatomas of the middle ear and the mastoid.

Forty cases of failed combined approach tympanoplasty were analysed. The commonest cause of failure was adhesions between the facial ridge and the tympanic membrane, causing segmental attico-mastoid malaeration in 51.3 per cent of cases followed-up continually. Other causes were, large dermoids, incomplete removal of squamous epithelium, and eustachian tube obstruction. Eustachian tube dysfunction did not appear to be a major cause of failure.

Cholesteatoma, Middle Ear↗
PubMed1992

Long-term results of total ossicular chain reconstruction using autografts.

The long-term results of 63 total ossicular chain reconstructions using autografts is presented. The follow-up period ranged from 18 months to 18 years with an average of 8.5 years. The primary aims of the study were firstly to assess the long-term success rate and to find out if there were any hitherto unknown causes of bone graft failure. In the event, it was found that the recently described anatomical variation of the oval window viz., the deep oval window, was the prime cause of failure in 32 per cent of unsuccessful cases. Some measures to help to mitigate this problem, are suggested. The result were assessed on the basis of: 1. A minimum gain of 20 dB HL in air conduction (Technical success). The success rate was 55.5 per cent. 2. Patients benefited using Smyth and Patterson's criteria in conjunction with the Glasgow Benefit Plot; 54 per cent of the patients benefited significantly.

Adolescent↗
PubMed1991

The deep oval window.

This article presents the results of an analysis of the variable and surgically important relationship between the oval window, the fossular walls and the related posterior tympanic recesses in 50 temporal bones. The visual impressions of superficial and deep oval windows seem to correspond fairly closely to the depth of the inferior wall of the fossula fenestra vestibuli (FFV). The depth of the superior and anterior walls of the FFV by themselves, did not appear to have such a dominating relationship in determining the deep oval window. There does not appear to be a well defined posterior wall in the vast majority of the specimens (86 per cent). In the event of scar tissue forming between the superior, inferior and anterior walls, the gap between the postero-superior part of the promontory and the posterior tympanic wall (posterior communication) could allow aeration of the region of the deep oval window in such an instance. Closure of this gap by a solid shelf of ponticulus or scar tissue could cause a localized malaeration of the fossula in most cases of deep oval windows. This is an entirely new concept of the likely problems of malaeration of a deep oval window which could arise due to anatomical variations and of the possible safety valve mechanism which could prevent such malaeration and its consequences.

Humans↗
PubMed1991

The fate of bone grafts in deep oval windows.

The use of bone grafts for total ossicular chain reconstructions in patients with deep oval windows may result in varying degrees of absorption of the segment of the bone graft in the fossula fenestra vestibuli. The mechanism of bone absorption is described--a condition not described before.

Adolescent↗
PubMed1986

Tegmental and petromastoid defects in the temporal bone.

Fifty temporal bones were examined using the temporal bone dissecting microscope. 34 per cent were found to have defects in the tegmen and petromastoid segments, resulting in communications between the cranial cavity and the middle ear cleft. However, no defects were found in the overlying dura. This may have an important bearing on the intracranial spread of infection from the middle ear cleft, even in the absence of any bony destruction due to chronic middle ear disease.

Ear Diseases↗
PubMed1980

A double blind trial of terfenadine and placebo in hay fever using a substitution technique for non-responders.

A double-blind study of terfenadine and placebo in 110 patients suffering from hay fever (confirmed by skin tests) was conducted. A novel technique was applied using an escape envelope containing a reference drug which could be taken under controlled conditions if, after 48 hours, the patient experienced no relief. Significantly more patients on placebo opened the envelope than patients taking the active drug. Terfenadine was demonstrated to be an effective drug in hay fever and produced no more drowsiness than placebo.

Adult↗
PubMed1979

Post-traumatic tuberculoid leprosy. (A case report).

Inoculation Tuberculoid Leprosy has been described by various leprologists off and on and this mode of onset has been established. A case of tuberculoid leprosy over thumb, appearing after trauma in an Army recruit is described with the review of the literature.

Adult↗
PubMed1979

Study of non-lepromatous leprosy among Indian Armed Forces personnel.

Clinico-histopathological study of 50 cases of Non-lepromatous leprosy among Indian Armed Forces personnel is presented. Maximum cases were of Tuberculoid (TT) type. Thirty four individuals were having single lesions. Posterior aspect of elbow and medial aspect of forearm were the favourite sites. Both Indian and Ridley and Jopling classification was studied while classifying the lesions. The individuals belonged to almost all the states of India. All of them denied the history of contact with a known case of leprosy. The highest prevalent age group was between 20 to 30 years. Two cases of Tuberculoid and 3 of Maculo-anaesthetic leprosy were without involvement of nerves.

Adult↗