Severe arterial bleeding after percutaneous transhepatic cholangiographic drainage.
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Biomedical subjects
Publications and source records attributed to T Rösch.
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A large body of literature has accumulated showing endoscopic ultrasonography to be highly accurate in the locoregional staging of esophageal cancer. Several special aspects and problems of EUS in this setting are also presented in the literature. This article reviews this body of information and presents data from endoscopic staging research.
This article provides an overview of the articles published on locoregional staging of stomach cancer by endoscopic ultrasonography. For an analysis of the clinical value of EUS in the diagnosis and treatment, the reader is referred to the review books, articles, and consensus statements that are cited.
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Staging of pancreatic cancer is still considered to be one of the most difficult areas of endoscopic ultrasound (EUS) in gastroenterology. Variable scanning planes to obtain images of the tumor and its relationship to surrounding structures and vessels as well as a variety of possible artifacts in the scanning of pancreatic tumors greatly contribute to these difficulties. This review attempts to cover all relevant aspects of the literature regarding pancreatic cancer staging.
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This year's DDW again presented us with an extremely interesting and very up-to-date variety of endoscopic abstracts, dealing with established as well as new technology, and increasingly attempting to evaluate relevant issues such as cost-effectiveness and outcome. As is the case every year, the present DDW Congress Report faces the problem of how to cover all the abstracts accepted, while at the same time trying not to deal with them too superficially. The published endoscopic abstracts, the number of which has greatly increased, form the basis for this review, although an update for oral or poster presentation in San Diego may have changed the message in a few of them.
ES is certainly the most accurate technique presently available for visualizing small lesions in the pancreas and (distal) bile duct. However, this technique can at present not be utilized for improving the earlier diagnosis of pancreatic carcinoma but is of great help in the preoperative localization of pancreatic endocrine tumours. ES makes significant contributions to the preoperative loco-regional staging of pancreatic, ampullary and distal biliary malignancies, but it has distinct limitations in large masses and more remote areas (superior mesenteric vein) and in the differentiation between malignant and inflammatory lesions.
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In a prospective clinical study (March 89-June 91), we examined 114 infertile women to evaluate the diagnostic value of trans-uterine tubal cannulation with the injection of sterile fluid and consecutive sonographical control in the assessment of tubal patency. The results of this technique were compared with the findings of laparoscopy and/or hysterosalpingography. With the Jansen-Anderson Catheter (J-A-C) it was possible to reach the isthmic part of the tube without any analgesia or anaesthesia. 10 to 15 ml of sterile culture medium were injected. In case of tubal patency the fluid was detectable in the pouch of Douglas by transvaginal ultrasound. In 108 out of 114 women (94.7%), the cannulation of at least one tube was possible. All 97 patients with patent tubes (laparoscopy) were diagnosed correctly via the J-A-C. The three cases of proximal tubal occlusion were also diagnosed correctly, 8 patients with one or two-sided hydrosalpinx were also recognized. All five patients with bilateral hydrosalpinx were detected. Three women showed a unilateral hydrosalpinx in the laparoscopy. In these cases the diagnosis obtained by the J-A-C was once bilaterally patent and twice bilaterally distally occluded. Trans-uterine cannulation of the tubes with injection of sterile fluid and consecutive transvaginal sonography is an easy and safe method to evaluate the tubal status. It becomes possible thereby to prove tubal patency in a very early stage of diagnostics. Loss of time and futile treatment cycles (stimulations or inseminations in cases of tubal occlusion) can thus be avoided.
Gastrointestinal endoscopy continues to play a significant role in gastroenterologic oncology. As a diagnostic tool, it has largely replaced radiology in diseases of the gastrointestinal tract because of its capability to provide a tissue diagnosis by endoscopic biopsy. The still-expanding therapeutic potential of gastrointestinal endoscopy represents the prototype of minimal invasive therapy. This review deals with relevant papers on diagnostic and therapeutic gastrointestinal endoscopy during the past 2 years. The abundance of studies renders a detailed discussion of all or even most of them impossible; therefore, only trends are shown. The reader is referred to the annotations in the reference list for more detailed information.
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Symptomatic pancreas tumors are diagnosed in general by ERCP, transabdominal ultrasonography, and computed tomography. Endoscopic ultrasonography, angiography (facultative) and video laparoscopy in combination with laparoscopic sonography and peritoneal lavage are providing preoperatively important additional information about the spreading of the tumor. Preoperative diagnostic procedures should allow the surgeon to exclude patients with an unresectable tumor from extended resection. In most of these patients satisfactory palliation can be achieved endoscopically. The indication for surgical treatment of resectable pancreatic tumors is based on the mortality of pancreaticoduodenectomy far beyond 5% in experienced centers. Improved surgical techniques and improved perioperative management together with the implementation of accurate preoperative analysis of risk factors allow resection of primary pancreatic tumors with a low morbidity and mortality.
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Endoscopic ultrasonography (EUS) has been developed for high resolution imaging of the upper gastrointestinal tract and immediate surroundings, such as the pancreas and the biliary tract. The ultrasonic transducer at the tip of the instrument works with ultrasound frequencies of 7.5 MHz and provides delineation of small structures and lesions, but the ultrasonic penetration depth is not sufficient for visualization of organs such as liver, spleen and kidneys. In the diagnosis of pancreatic disease the advantages of EUS lie in the delineation of small endocrine and exocrine tumors of the pancreas, complementary to other procedures such as ultrasound, CT and ERCP. EUS is also the most accurate single diagnostic method in the local staging of pancreatic ampullary carcinoma, being superior to other modalities in the diagnosis of portal venous infiltration. The disadvantage of EUS is its poor ability to differentiate between malignant and focal inflammatory tumors of the pancreas. The role of EUS in the diagnosis of chronic pancreatitis has not yet been fully established.
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