T Raasakka | PubMed Health

PubMed1978

Cardiac involvement in polymyositis.

Sixteen cases of polymyositis (PM) were treated at the Central Hospital, Jyväskylä. Features of cardiac involvement were observed in 11 cases (69%). The heart diseases which developed or worsened after the onset of PM were grouped as follows: (1) Sole disturbance of conduction--one case, (2) congestive heart failure--four cases, (3) coronary heart disease with or without congestive heart failure--six cases. Three patients suffered an acute myocardial infarction. Electrocardiography revealed arrhythmias in eight cases and disturbances of conduction in three. In one patient complete atrioventricular block and congestive heart failure necesssitated installation of an intracardiac pacemaker. In four patients congestive heart failure progressed to death. In two autopsied cases changes suggestive of PM were found in the heart muscle. Involvement of the heart in PM was prognostically a bad sign.

Adolescent↗

PubMedDate not supplied

Fatal cardiac arrhythmia after oral sumatriptan.

Typically, 3% to 5% of patients experience sensations of heaviness, pressure, and tightness in the chest after administration of sumatriptan, but there is little ECG evidence of ischemia. The serious cardiovascular incidents after consuming sumatriptan have been associated mostly with the subcutaneous dosage form of this drug and with patients with underlying cardiovascular risk factors. We report a case of fatal cardiac arrhythmia in an otherwise perfectly healthy patient with migraine after consuming a single 100-mg dose of oral sumatriptan.

Administration, Oral↗