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Biomedical subjects

T Ramakrishnan

Publications and source records attributed to T Ramakrishnan.

54 records · Page 3Linked to original sources
PubMed1966

Biosynthesis of nucleic acid purines in Mycobacterium tuberculosis H37Rv.

1. The biosynthesis of nucleic acid purine in Mycobacterium tuberculosis H(37)R(v) has been studied by using (14)C-labelled precursors. 2. The results indicate that C-2 and C-8 of the purine ring are derived most efficiently from serine and glycine and not from formate. 3. [(14)C]Methionine is not incorporated into the ureide carbon atoms of the purine ring.

Chromatography, Ion Exchange↗
PubMedDate not supplied

Beneficial effects of fasting and low carbohydrate diet in D-lactic acidosis associated with short-bowel syndrome.

A case of D-lactic acidosis in an 18-yr-old man with a short bowel is reported. The diagnosis, suspected on clinical grounds, was confirmed by serum and urine levels of D-lactate. Our studies revealed that an ad libitum diet was associated with elevated D-lactate levels and "nothing per oral" and 10% carbohydrate diet regimens caused a drop in D-lactate levels. We recommend npo and low carbohydrate diet as preferred alternatives to antibiotics in some patients with D-lactic acidosis. The literature is reviewed.

Acidosis↗