[Hyperuricemia and gout].
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Biomedical subjects
Publications and source records attributed to T Rodríguez Ruiz.
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We report a prospective study of the cases of acute diarrhea admitted to our pediatric service during one year (n = 172) to elaborate a screening method to identify patients with bacterial diarrhea. A bacterial causative organism was identified in 31.4%. The most common species was Salmonella, followed by Campylobacter. We evaluated the clinical presentation parameters, looking for differences between the group were a bacterial organism was isolated and in the group where it was not. We designated a score valid as a first level screening for bacterial diarrhea. With a score greater than or equal to 7 the sensitivity was 81.5% and the specificity 60.2%. The latter increased to 95% when occult blood in feces was associated with the greater than or equal to 7 score (second screening level). We propose this clinical score as a criterion for the indication of fecal cultures in children with acute gastroenteritis.
The disease caused by the deposition of dehydrated calcium pyrophosphate crystals (chondrocalcinosis) is a metabolic joint disease poorly known outside rheumatologic media. It is estimated that about 5% of the adult population has deposits in the knees and that prevalence increases with age. The incidence of symptomatic disease is about the same as that of gout. The clinical presentation is variable, from pseudogouty forms, pseudorheumatoid arthritis or secondary degenerative joint disease, to 20% of asymptomatic cases. In the systematic evaluation family history should be sought, and metabolic diseases such as gout, diabetes, hemochromatosis, hyperparathyroidism and hypothyroidism should be ruled out. The condition is treated with nonsteroidal antiinflammatory drugs, and although the outcome is generally favorable, severe destructive joint disease may develop. In the present article we review this condition on the basis of the presentation forms of 10 of our patients.