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T S Edwards

Publications and source records attributed to T S Edwards.

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Dental status of 12-year-olds treated in private practice and a school dental service.

Different ways of service provision frequently lead to different services being provided. In the School Dental Service (SDS) in Western Australia, all 5-15-yr-olds are eligible for care free of charge and most avail themselves of the service. The parents of some children choose to use private dentists (typically copaying about 50% of the cost) and their children do not attend the SDS. This study aimed to compare the dental status of 12-yr-olds who attended private dentists with that of matched children enrolled in the SDS. Non-enrolled 12-yr-olds in Perth (F- 0.8 mg/l) were identified and asked to provide background information and participate in clinical examinations. Each non-enrolled participant was matched with a classmate of the same sex. Of 184 non-enrolled children, 100 actually participated. Data on caries experience (DMFT and DMFS), fissure sealants and gingival health (CPITN) were collected by clinical examination. Analyses used Wilcoxon's signed rank, categorical and t-tests and simple linear regression. Caries prevalence was lower in non-enrolled children (0.31) than in enrolled (0.47). Caries experience was also lower in non-enrolled children (mean DMFT 0.71 vs. 0.95, ns). Enrolled children had more FT than non-enrolled (Wilcoxon, P = 0.059) but the mean number of DT in each group was 0.14. Enrolled children had somewhat fewer fissure sealants than non-enrolled children but in enrolled children there was an apparent (P = 0.056) inverse relationship between number of fissure sealants and DMFT scores; this was not the case in the non-enrolled group, suggesting better targeting of fissure sealants in the SDS.(ABSTRACT TRUNCATED AT 250 WORDS)

Chi-Square Distribution

Characterization of a polyvalent antibody directed against the IgG Fc receptor of human mononuclear phagocytes.

We have raised an antibody to the IgG Fc receptor (FcR) of human mononuclear phagocytes by immunizing a goat with FcR purified by ligand affinity from a human monocyte line (U937). This antiserum, which inhibited the binding of IgG ligand to the receptors on U937, precipitated from detergent lysates of surface-radioiodinated U937 cells a 72 Kd sialoglycoprotein (p72) identified as the FcR by several previously published criteria. Two other bands seen in autoradiograms of SDS gels were precipitated by this antiserum: a 40 to 43 Kd band that co-purified with p72 and a 170 Kd protein that was not present in the immunogen. Fractionation of the IgG of this antiserum into two subclasses yielded one subclass (IgG1) in which anti-p72 activity was considerably enriched relative to antibody activities against other molecules. This antiserum precipitated p72 not only from U937 but from HL60 cells and from human peripheral blood monocytes as well, indicating common antigens on the p72 molecules from these three cells. However, p72 was not recovered from lysates of surface-iodinated human polymorphonuclear leukocytes or murine macrophage lines. Anti-p72 activity was not completely removed by adsorption with intact U937, suggesting that the antiserum recognizes portions of p72 that are not exteriorly disposed, perhaps noncarbohydrate portions of the molecule. We expect this antiserum to be useful for a number of studies of receptor structure and function.

Animals

Fibre-optics.

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Dental Equipment