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Biomedical subjects

T S Horowitz

Publications and source records attributed to T S Horowitz.

4 recordsLinked to original sources
PubMed2001

Efficacy of bright light and sleep/darkness scheduling in alleviating circadian maladaptation to night work.

We tested the hypothesis that circadian adaptation to night work is best achieved by combining bright light during the night shift and scheduled sleep in darkness. Fifty-four subjects participated in a shift work simulation of 4 day and 3 night shifts followed by a 38-h constant routine (CR). Subjects received 2,500 lux (Bright Light) or 150 lux (Room Light) during night shifts and were scheduled to sleep (at home in darkened bedrooms) from 0800 to 1600 (Fixed Sleep) or ad libitum (Free Sleep). Dim light melatonin onset (DLMO) was measured before and after the night shifts. Both Fixed Sleep and Bright Light conditions significantly phase delayed DLMO. Treatments combined additively, with light leading to larger phase shifts. Free Sleep subjects who spontaneously adopted consistent sleep schedules adapted better than those who did not. Neither properly timed bright light nor fixed sleep schedules were consistently sufficient to shift the melatonin rhythm completely into the sleep episode. Scheduling of sleep/darkness should play a major role in prescriptions for overcoming shift work-related phase misalignment.

Adaptation, Physiological↗
PubMed2001

Search for multiple targets: remember the targets, forget the search.

Models of visual search performance typically assume that search proceeds by sampling without replacement. This requires memory for each deployment of attention. We tested this assumption of memory-driven search using a multiple-target search paradigm. We held total set size constant, varied the number of targets in the display, and asked subjects to report whether or not there were at least n targets present, where n was varied by block. This allowed us to measure the time to find each subsequent target. Memory-driven search predicts that reaction time should be a linear function of n. The alternative memory-free search hypothesis predicts an accelerating function. The data falsify the memory-driven hypothesis. They were consistent with the memory-free search hypothesis but would also be consistent with memory for a small number of previously attended locations.

Attention↗
PubMed1998

Visual search has no memory.

Humans spend a lot of time searching for things, such as roadside traffic signs, soccer balls or tumours in mammograms. These tasks involve the deployment of attention from one item in the visual field to the next. Common sense suggests that rejected items should be noted in some fashion so that effort is not expended in re-examining items that have been attended to and rejected. However, common sense is wrong. Here we asked human observers to search for a letter 'T' among letters 'L'. This search demands visual attention and normally proceeds at a rate of 20-30 milliseconds per item. In the critical condition, we randomly relocated all letters every 111 milliseconds. This made it impossible for the subjects to keep track of the progress of the search. Nevertheless, the efficiency of the search was unchanged. Theories of visual search all assume that search relies on accumulating information about the identity of objects over time. Such theories predict that search efficiency will be drastically reduced if the scene is continually shuffled while the observer is trying to search through it. As we show that efficiency is not impaired, the standard theories must be revised.

Humans↗