PubMed Health⌕ Search

Biomedical subjects

T S Micolonghi

Publications and source records attributed to T S Micolonghi.

4 recordsLinked to original sources

Ruptured mesenteric varices in hepatic cirrhosis: a rare cause of intraperitoneal hemorrhage.

We report a case of massive and fatal intraperitoneal hemorrhage from ruptured superior mesenteric varices secondary to portal hypertension and hepatic cirrhosis and proved by postmortem angioradiography. To our knowledge, this is the second case in the English language literature. Although very rare, this possibility should be borne in mind when one attempts to locate hemorrhagic complications of portal hypertension.

Autopsy↗

Localized large cell lymphoma cured by simple excision.

Diffuse large cell lymphoma is frequently localized at the time of presentation, but the aggressive natural history of the disease in most patients has suggested that extensive and intensive radiation and/or chemotherapy is necessary to control this disease. We describe a patient who has remained free of disease for 20 years after simple excision of a diffuse large cell lymphoma localized to the right cervical region. Review of the biopsy material showed characteristic histological features suggestive of an orderly growth pattern of tumor cells as well as sclerosis. The clinical course of this patient after minimal therapy emphasizes the possibility of long survival with localized large cell lymphoma and suggests that the characteristic morphologic features observed in this case should be sought in other cases, since it may imply a favourable prognosis.

Cell Nucleolus↗

Vasculitis and Sjögren's syndrome with IgA-IgG cryoglobulinemia terminating in immunoblastic sarcoma.

Generalized lymphadenopathy and other manifestations of Sjögren's syndrome developed in a 68 year old woman with a long history of systemic vasculitis and arthralgia. An unusual immunologic feature was hypogammaglobulinemia and immunoglobulin A (IgA) monoclonal immunoglobulinemia with mixed IgA-IgG cryoglobulin. At autopsy, the histopathologic findings were compatible with immunoblastic sarcoma. The monoclonal IgA protein, found in serum, pleural and pericardial fluids, showed rheumatoid factor activity. Immunocytes from the immunoblastic sarcoma were found to be the source of the monoclonal IgA protein.

Aged↗