Biomedical subjects

T S Tsyb

Publications and source records attributed to T S Tsyb.

7 recordsLinked to original sources

PubMed1987

Contribution of a photoreactivable component to the oxygen effect observed in certain rad mutants of Saccharomyces cerevisiae after exposure to high energy electrons.

It is shown that a fraction of damage induced by high energy electrons (25 MeV) in certain rad mutants of the yeast Saccharomyces cerevisiae can be photoreactivated. The photoreactivable damage contributes to the lethal effect of this type of irradiation and modifies the oxygen effect. Using photoreactivating light or nigrosin, the amount of photoreactivable damage is reduced and the oxygen enhancement ratio (OER) for yeast mutants increases approximately to the OER found in wild-type cells.

Aerobiosis↗

PubMedDate not supplied

[Biological effectiveness of pulsed and continuous neutron radiation for Saccharomyces yeast cells].

The article presents the data on biological effectiveness of neutrons generated by the pulsed reactor BARS-6 (dose-rate up to 6 x 10(6) Gy/s) in comparison with fast neutrons of the reactor BR-10 (dose-rate 6.3 x 10(-2) Gy/s). It was shown for yeast cells of a wild type that the RBE values of pulsed neutrons varied insignificantly with a dose (2.0-1.7) white for continuous neutron irradiation clear RBE dependence on the dose was observed. It was also found that the yeast cells had identical capability of postirradiation recovery in non-nutrient medium (LHR) following both gamma-irradiation and neutron exposure irrespective of neutron dose-rate.

Gamma Rays↗

PubMedDate not supplied

[Photoreactivation in Saccharomyces cerevisiae cells after irradiation with electrons (25 MeV). The role of photoreactivated damage in the manifestation of oxygen effects in radio- and UV-sensitive mutants of Saccharomyces cerevisiae].

Significant photoreactivation was noted in radio- and UV-sensitive rad-mutants of Saccharomyces cerevisiae cells exposed to 25 MeV electrons. In order to make the photoreactivable damage be manifest anoxic conditions of irradiation should be chosen as optimal ones. It was shown that the low oxygen effect was partially associated with the photoreactivable damage involved in the lethal effect of ionizing radiation.

Electrons↗

PubMedDate not supplied

[Experimental basis for the use of a lawn, different in relation to the 1st host, for determining the viability of UV-irradiated phage-bacterium complexes].

Explore the source record for details and available documents.

Bacteriological Techniques↗

PubMedDate not supplied

[Decrease in the survivability of T1 bacteriophage subjected to UV-irradiation in the early stages of infection of Escherichia coli B cells].

Explore the source record for details and available documents.

Coliphages↗

PubMedDate not supplied

[Characteristics of the photoreactivation of bacteriophage T-1 irradiated in the form of complexes with E. coli B cells at early stages of infection].

Explore the source record for details and available documents.

Cell Membrane↗

PubMedDate not supplied

[Current problems of neutron radiobiology].

A brief review of up-date problems of neutron radiobiology, related to neutron therapy development and setting up of radiation safety standards for neutrons, is present. The main attention is paid to the effects of combined gamma-neutron irradiation, peculiarities of reactor neutrons biological action and new approaches in neutron capture therapy. On the basis of own and literature data the results of cellular and whole-body studies as well as the applicability of biophysical modelling for description and interpretation of experimental data are discussed.

Animals↗