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Biomedical subjects

T Sabesan

Publications and source records attributed to T Sabesan.

13 recordsLinked to original sources

Malignant fibrous histiocytoma: outcome of tumours in the head and neck compared with those in the trunk and extremities.

Malignant fibrous histiocytoma is one of the commonest soft tissue sarcomas in adults, affecting, in order of frequency, the extremities, trunk and head and neck. We treated 131 patients with malignant fibrous histiocytoma by radical, wide, or marginal resection. Their mean age was 43 years, and there were 54 in the head and neck and 77 in the trunk and extremities. The extent of clearance of the tumour, local recurrence, and 5-year survival were studied in these two groups. In the head and neck group, local recurrences developed in 86% after marginal resection, 66% after wide resection and 27% after radical resection. The comparative figures in the trunk and extremities group were 75, 71 and 18%, respectively. The overall 5-year survival was 48% in the head and neck group and 77% in the trunk and extremities group (p=0.03). Repeat operations for recurrences of tumour offered a 'cure rate' of 23% in the head and neck group and 61% in the trunk and extremities group. Inadequate resection of the sarcoma in the head and neck was associated with a high incidence of local recurrence and a poor prognosis. Therefore, we suggest that the initial operation for sarcoma in the head and neck should be as radical as possible to reduce the chance of local recurrence and to improve the outcome.

Adolescent↗

Anthropometric analysis of eyebrows and eyelids: an inter-racial study.

The shape of the eyebrow and upper eyelid are distinctive facial landmarks. In cosmetic and reconstructive operations, maintenance of the anatomical relations of these landmarks ensures a pleasing postoperative appearance. The measurements differ, however, among different ethnic groups. We studied the position of the eyebrow and eyelids in three different racial groups, white, Indian, and Chinese. The aim of the study was to quantify the position of the eyebrow and eyelids and to find out if there were significant differences among the races.

Adolescent↗

Another use of the Foley catheter: retraction for operations on the floor of mouth and ventral aspect of the tongue.

A Foley catheter that is passed through the nose and sutured to the tip of the tongue can be used to facilitate retraction for operations on lesions on the ventral aspect of the tongue and the floor of the mouth. It provides excellent access and is simple, inexpensive, atraumatic, minimises frustration, reduces the operating time, and eliminates some of the difficulties associated with the use of metal retractors.

Catheterization↗

Angiolymphoid hyperplasia with eosinophilia masquerading as Kimura disease.

Angiolymphoid hyperplasia with eosinophilia is a rare benign vasoproliferative disease of unknown cause, which can present as tumour-like nodules in the head and neck. We treated a patient who showed some of the features of Kimura disease (KD), which is an important differential diagnosis, because of the latter's association with renal disease.

Adult↗

Intraosseous vascular anomaly (haemangioma) of the zygoma.

Intraosseous vascular anomalies are rare, and although they have been described in the facial skeleton, those occurring in the zygomatic bone are extremely rare. We report the case of a 38-year-old woman who presented with a painless hard swelling in the left zygomatic prominence, which was diagnosed as a cavernous haemangioma after a bone biopsy. The further management of this lesion in discussed, with particular reference to surgical resection and reconstruction.

Adult↗

Subdural empyema and herpes zoster syndrome (Hunt syndrome) complicating removal of third molars.

We report a case of subdural empyema and herpes zoster syndrome (Hunt syndrome) complicating routine removal of third molars. Subdural empyema is an extremely rare but life-threatening complication of dental sepsis arising spontaneously or after dental surgery. The clinician should be familiar with its presentation and have a high index of suspicion, because late recognition and delay in its treatment can increase the associated morbidity and mortality. Surgical procedures and in particular maxillofacial surgery have also been known to trigger varicella zoster reactivation resulting in Hunt syndrome. Some patients develop the characteristic rash several days after the onset of facial weakness, so that Hunt syndrome may initially be misdiagnosed as Bell's palsy. We highlight the difficulties in diagnosing Hunt syndrome and argue the case for early treatment of all patients with Hunt syndrome and Bell's palsy with a combination of systemic steroids and antiviral drugs.

Adult↗