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Biomedical subjects

T Sagát

Publications and source records attributed to T Sagát.

At least 19 recordsLinked to original sources

Ciprofloxacin in treatment of nosocomial meningitis in neonates and in infants: report of 12 cases and review.

Twelve cases of neonatal and infant nosocomial meningitis treated with intravenous ciprofloxacin in doses of 10 to 60 mg/kg/day are described. Four neonates were 21 to 28 days old and eight infants were 2 to 6 months old. Six presented with Gram-negative meningitis: Escherichia coli (2), Salmonella enteritidis (1), Acinetobacter calcoaceticus (1), two with two organisms, and (H. influenzae plus Staphylococcus epidermidis, Acinetobacter spp. plus S. epidermidis), and six were attributable to Gram-positive cocci (four S. aureus and two Enterococcus faecalis). Ten cases were cured. In two cases, reversible hydrocephalus appeared that responded to intraventricular punctures. In seven children, no neurologic sequellae appeared after a 2- to 4-year follow-up. One neonate had relapse of meningitis 3 months later and was ultimately cured, but developed a sequellae of psychomotoric retardation. Follow-up varied from 27 months to 10 years. Current published case reports from Medline on quinolone use in meningitis in neonates and infants are reviewed.

Anti-Infective Agents↗

[A rational diagnostic program for hypertension in children].

Early screening of subjects liable to develop cardiovascular diseases is one of the main tasks of preventive cardiology of child age. The authors present a rational programme for the screening and diagnostic of hypertension in children, its aim being to differentiate primary and the most frequent secondary forms of hypertension; this will create prerequisites for its adequate treatment (non-pharmacological and pharmacological) as well as for dispensarization. Review.

Adolescent↗

Treatment of renal hypertension in children by captopril.

Nine children aged 2 months to 13 (mean 6.6) years with renal hypertension were treated with captopril. The treatment lasted for 1.5 to 14 months. Maintenance doses ranged between 1 and 5 mg/kg/day. Good effect was achieved with captopril in children with normal renal function and in mild renal insufficiency. In patients with end-stage renal disease when dialysis failed to maintain normal body water captopril was ineffective.

Captopril↗

Pediatrical case histories analyzed by means of a computer.

The authors present their first version of the formation of anamnestic case histories (family, personal, epidemiological, and social) by means of a conversation between the physician and the computer. During the recording a set of the means of expression is used, this allows for an exhaustive compilation and recording of various types of case histories. The means of expression called variables make up the questionnaire sentence. The case histories- conversations about them, are presented by the algorithm of the questionnaire in logical sequences which permit suprabound jumps off to other linkages. The created complexes-sentences are verified as a whole and then recorded. Portions of different types of case histories are demonstrated in this paper together with their possible side jumps. The possibilities of computer analysis lie in repeated recording, corrections, in the formation of statistical analyses of various data and, in the future, also in the formation of differential diagnostic considerations with the assistance of computers.

Computers↗