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T Sen

Publications and source records attributed to T Sen.

28 records · Page 2Linked to original sources
PubMed1978

A study of three protocols of blood transfusion before renal transplantaion in the dog.

Three protocols of blood transfusion were evaluated in a canine model for (1) the strength and breadth of leukocytotoxin induction, (2) the induction of cell-mediated immunity against the blood donors, (3) haemagglutinin production, and (4) any effect on kidney graft survival. At the end of the transfusion schedule, each dog received a kindey graft and was given azathioprine and prednisolone postoperatively. All dogs were unrelated and blood donors were not used as kidney donors. All three transfusion protocols, comprising i.v. injections of blood twice weekly or every 2 weeks from one or three donors, induced unacceptably strong and broad leukocytotoxins. All transplants performed across a positive crossmatch failed to function. However, where a negative crossmatch was available, the trend of results was that the transfused dogs had better graft survival than nontransfused animals similarly treated with azathioprine and prednisolone. Only one dog produced haemagglutinins. Several animals had positive cell-mediated immunity against the blood donors, but the response was not strong and was frequently not sustained.

Animals↗
PubMed1977

Sucrose teepol tellurite agar: a new selective indicator medium for isolation of Vibrio species.

Sucrose teepol tellurite (STT) agar is a more successful medium in positive-recognition palting procedures than thiosulfate-citrate-bile salts-sucrose (TCBS) agar because STT agar yields higher isolation of typical colonies of Vibrio cholerae, which directly agglutinate in antiserum to V. cholerae, from patients and contacts infected with this organism. STT agar has a simple composition and, like TCBS agar, needs no sterilization. STT agar is highly selective for V. cholerae, nonagglutinating vibrios, and Vibrio parahaemolyticus. Growth of these bacteria from diarrhetic stool, from rectal swabs, and from stock cultures was compared on different media.

Agar↗
PubMed1974

Vibrio parahaemolyticus serotypes in Calcutta, India.

A study of V. parahaemolyticus strains isolated from different sources in Calcutta showed that the serotypes associated with human gastroenteritis do not frequently coincide with those of marine and non-marine isolates. Some atypical, complex, and new serotypes are reported.

Agglutination Tests↗
PubMedDate not supplied

Antiinflammatory evaluation of a Pluchea indica root extract.

A methanolic fraction of a chloroform extract of defatted Pluchea indica roots was investigated for its antiinflammatory potential against several models of inflammation. The extract showed significant inhibitory activity against carrageenin-, histamine-, serotonin-, hyaluronidase- and sodium urate-induced pedal inflammation. The extract inhibited protein exudation and leucocyte migration. The extract also inhibited carrageenin- and cotton pellet-induced granuloma formation as well as turpentine-induced joint oedema and adjuvant-induced polyarthritis. The present observations establish the efficacy of the extract in the exudative, proliferative and chronic stages of inflammation.

Adrenalectomy↗