[Acute myelofibrosis--case reports of acute megakaryoblastic leukemia and acute myeloblastic leukemia].
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Acute Disease↗
Biomedical subjects
T Shichishima
Publications and source records attributed to T Shichishima.
[Involvement of eosinophils in leukemic clones: cytogenetic study in eosinophilic colonies from acute myelogenous leukemia associated with 8;21 translocation].
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Chromosomes, Human, 21-22 and Y↗
[A case of acute myelomonocytic leukemia with bone marrow eosinophilia, associated with pericentric inversion of chromosome 16].
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Chromosome Inversion↗
[A family study of storage pool disease].
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Adenine Nucleotides↗
Erythroid precursor cells in patients with paroxysmal nocturnal hemoglobinuria.
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Adult↗
[Anemia with chronic myelocytic leukemia].
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Anemia↗
[An autopsy case of chronic myelogenous leukemia with megakaryoblastic transformation].
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Aged↗
[Hematopoietic stem cells in chronic rheumatoid arthritis].
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Adult↗
[A case of preleukemic states terminating in acute myelomonocytic leukemia].
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Adult↗
[Two cases of priapism complicating chronic myeloid leukemia. Chronic phase and blastic crisis after splenectomy].
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Adult↗
[A case of adult T-cell leukemia with a huge splenomegaly, pancytopenia and prolymphocytosis after splenectomy].
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Adult↗
[Prevalence and causes of iron deficiency in Japanese women (author's transl)].
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Adolescent↗
[Sjögren's syndrome associated with a benign thymic tumor: report of a case with wide spectrum of clinical feature (author's transl)].
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Adult↗
[A case of IgA-kappa type extra-medullary plasmacytoma associated with polyneuropathy and other various symptoms (author's transl)].
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Dysgammaglobulinemia↗
Case of a child with paroxysmal nocturnal hemoglobinuria diagnosed by flow cytometry.
A case of a child with paroxysmal nocturnal hemoglobinuria (PNH) is characterized by an increased sensitivity of the erythrocyte to hemolytic action of complement. The widely used Ham test may not always be reliable. Recently, a panel of monoclonal antibodies has become available to detect various glycosylphosphatidylinositol (GPI)-linked proteins by flow cytometry (FCM) and the deficiency of GPI-anchored proteins on the various kinds of cell membranes is implicated as the pathogenesis of PNH. We diagnosed a case of a child with PNH by FCM and complement lysis sensitivity (CLS) test, which showed the increased sensitivity of PNH erythrocytes to complement. His diagnosis was delayed because of Ham test negativity and rarity of PNH cases in children.
Child↗