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Biomedical subjects

T Shwe

Publications and source records attributed to T Shwe.

23 records · Page 2Linked to original sources
PubMedDate not supplied

Prevalence of colour blindness among patients with leprosy.

Using Ishihara test plates the prevalence of colour blindness was studied on six hundred and ninety-seven leprosy patients and two hundred and ninety-two normal healthy controls. 7.88% of male patients with tuberculoid leprosy, 12.18% of male patients with lepromatous leprosy, and 0.67% of male controls were detected to be colour blind (red-green deficiency or total colour weakness). The differences between the different groups are significant. Among female patients and controls, only one lepromatous leprosy patient was detected to have red-green deficiency. This suggests the possibility of a genetic predisposition to Mycobacterium leprae infection in patients with leprosy.

Color Vision Defects↗
PubMedDate not supplied

The effect of tetanus toxoid in leprosy patients.

Since cases of lepra reaction following smallpox vaccination and BCG vaccination had been reported the effect of tetanus immunisation on leprosy patients (whether it may provoke a lepra reaction or not) was studied. Three doses of purified tetanus toxoid (one ml initially, one ml after six weeks and one ml after six months) were given to 357 leprosy patients and 60 patients living in the same environ were followed as controls. The antibody response following immunisation was followed in six lepromatous leprosy patients using toxin antitoxin neutralisation test at the Lf/1000 level in mice and in three of them the antibody titre of leprosy patients rose to satisfactory level. The number of lepra reactions in these patients was monitored for nine months (two months before vaccination, during the six months period of vaccination and one month after the last dose of vaccine). There was no significant rise in the number of patients with reaction following the vaccination.

Antibodies, Bacterial↗