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Biomedical subjects

T Silva

Publications and source records attributed to T Silva.

30 records · Page 2Linked to original sources

Halothane anesthesia and serum electrolytes.

The disparate observations on the effect of halothane anesthesia on the serum electrolyte levels in humans prompted us to carry out this work. In this study the levels of sodium, potassium, magnesium, calcium, chloride and inorganic phosphorus were determined in serum of 25 male and 15 female patients, with an age range of 15 to 40 years, who had various pathologies requiring surgery and who were given halothane anesthesia. Significant difference were detected in the concentrations of sodium, potassium, calcium and inorganic phosphorus between presurgical and post-anesthesia induction samples. The truly striking finding in the present study was the significant increase in serum inorganic phosphorus in the intra-operative period. It is suspected that this increase is due to a defect in phosphorylating mechanisms which leads to a rapid hydrolysis of stored and preformed ATP.

Adolescent↗

Effect of isofluorane anesthesia on serum levels of Zn, Cu, Fe, Mn and Co in humans.

In this study the levels of zinc, copper, iron, manganese and cobalt were determined in serum of 25 male and 15 female patients, aged 18 to 35 years, with various pathologies requiring surgery, and who had received isofluorane anesthesia. Significant differences were detected in the concentration of zinc, copper, iron and manganese between presurgical and post-anesthesia samples. The truly striking finding in the present study was the significant increase in serum Zn in the post-operative period. The fact that alterations in the serum levels of these elements occurred only after a considerable time had elapsed following the intervention (24 hours), leads to the conclusion that the changes in serum cation concentration very likely result from surgical trauma and not from isofluorane anesthesia per se.

Adolescent↗

Manganese levels in serum of healthy Venezuelan infants living in Mérida.

Taking up where a previous paper had left off (10) the purpose of this study was to examine in further detail the serum concentration of manganese of 180 apparently healthy Venezuelan infants (96 boys and 84 girls) ranging from 5 days to 12 months old, all residents of Mérida. The flow injection analysis-atomic absorption spectrophotometric technique was used for the determination of manganese. The mean values of serum manganese were 0.42 +/- 0.12, 0.41 +/- 0.11, 0.39 +/- 0.13, 0.39 +/- 0.1, 0.38 +/- 0.09, 0.37 +/- 0.11, 0.36 +/- 0.12 and 0.29 +/- 0.10 microgram/L in infants 5 days and 1,3,5,7,10,11 and 12 months old, respectively. These values indicate that the average concentration of manganese in serum decreases with age, but the mechanism involved is not yet known, nor are the consequences of the decrease. The statistical analysis did not show any significant influence of sex on the serum value of the metal in the age range of 5 days to 12 months.

Age Factors↗

Health survey of workers occupationally exposed to cobalt.

The results are presented for a health control program using 236 male workers exposed to a cobalt inhalation risk. The study group consisted of grinders, producers of diamond tools, workers in metallurgical and mechanical industries (where Widia tools are processed and sharpened), and finally formerly exposed workers. All subjects received a clinical examination, the European Community for Coal and Steel questionnaire on respiratory complaints, a chest X-ray, pulmonary function test, electrocardiogram and determination of urinary cobalt; in 91 subjects, the metacholine bronchial provocation test was performed. Three cases of interstitial lung disease were identified. There were no cases with a significant alteration of ventilatory function while 20 cases (16 exposed and four formerly exposed workers) showed a reduced carbon monoxide transfer coefficient (TL,CO,sb/Va).

Bronchial Provocation Tests↗

Rupture of the plantar fascia in athletes.

Symptoms resembling those of plantar fasciitis were seen in six athletes who were thought to have a partial rupture of the plantar fascia. Treatment, which included the use of crutches, anti-inflammatory agents, strapping of the arch, and ice packs, was successful in all but one patient who had a painful mass in the area of the previous rupture. After surgical excision of the painful mass and release of the fascia, he recovered. Five of the six athletes had been previously treated with repeated local injections of steroid.

Adult↗

[Clinico-anamnestic survey in health professionals exposed to volatile anesthetics].

The authors describe the results of a preliminary clinical survey of a group of 220 health workers, physicians and 151 nursing and auxiliary staff members of a large regional hospital in Lombardia, who are exposed to volatile anaesthetics. Contact dermatitis, varices of the legs and arthrosis, particularly that of the cervical and lumbar tract, are the most frequently reported disease in our population. In 75% of cases these disturbances arose after the beginning of the job working in the operating-theatres. When compared with a control group there was a statistically significant difference for contact dermatitis (p less than 0.01) and cervical tract arthrosis (p less than 0.02). The statistical comparison among the subjects exposed to the anaesthetics gases, who were stratified on the basis of the level of exposure and of seniority, confirms a higher prevalence of symptoms due to a reduction of alertness and of psychological and psychomotorial performances in the more exposed personnel. The comparison between female staff exposed and not-exposed to the gases did not show an increase of abortivity, while a statistically significant difference was evident between the female staff (either exposed or not-exposed) and the wives of male workers not exposed to the anaesthetics gases.

Adult↗

[Sanitary surveillance of workers occupationally exposed to volatile anesthetics: proposal for a computerized program for data collection and processing].

The aim of this work is to present a computerized program for an epidemiological evaluation of the data relevant to workers occupationally exposed to anesthetic gases and of the related occupational risks. The great handiness, the speed of execution, the possibility of carrying out researches by mean of multiple variables correlation and the prompt availability of the data, are the distinguishing features of this program.

Air Pollutants, Occupational↗

Effect of dietary protein deficiency on the performance of turkeys and chickens.

Two field occurrences of protein-deficiency disease were reported in turkeys and chickens. The disease caused unthriftiness, poor growth, and the exhibition of pica in flocks of 15-week-old pedigree large white turkeys, and it resulted in a sharp drop (18%) in egg production in a flock of 60-week-old white leghorn layers. In each case, the disease was cured by replacing the protein-deficient diet with a protein-sufficient one.

Animals↗