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Biomedical subjects

T Snaprud

Publications and source records attributed to T Snaprud.

4 recordsLinked to original sources

[Oxygen therapy of patients with chronic obstructive pulmonary disease reduces the development of pulmonary hypertension].

The development of secondary pulmonary hypertension in patients with chronic obstructive pulmonary disease worsens their prognosis; oxygen therapy seems to improve prognosis in these patients. We measured the effect of oxygen therapy on mean pulmonary artery pressure in four women and four men aged 64 to 82 years (average 73 years) with chronic obstructive pulmonary disease. A right cardiac catheterisation was performed before and on average 11 months (8-16 months) after start of oxygen therapy. The mean pulmonary artery pressure decreased on average 5 mm Hg, from 24 to 19 mm Hg. As prognosis seems to be associated with pulmonary artery pressure, more patients with chronic obstructive pulmonary disease should be evaluated for oxygen therapy.

Aged↗

Arrhythmias in subjects with and without a history of palpitations: the Tromsø Study.

The study looked at palpitations in relation to the prevalence of arrhythmia, as assessed by 24-h ambulatory electrocardiography (ECG) in a population sample. The subjects were randomly drawn from among those involved in a cardiovascular survey. Forty-three of those who answered 'Yes' and 54 of those who answered 'No' (84% of those eligible) to the following question, participated: 'Have you observed sudden changes in your heart rate or heart rhythm during the preceding year?' In both groups mean age was 49 years and 58% were men. There was no relationship between recorded arrhythmia and perceived palpitations during monitoring. The prevalence of at least one arrhythmic episode (ventricular or supraventricular arrhythmia or pauses > = 1.5 s) was significantly higher in those who had perceived palpitations during the previous year (98%) than in those who had not (74%) (P < 0.0014). Through a simple question about palpitations during the preceding year we were able to identify significantly a population with true arrhythmias. However, the question could not be used to define a population entirely without arrhythmia. The high prevalence of arrhythmia in subjects without reported palpitations indicates that it is a normal finding which alone should not demand further clinical investigations.

Adult↗

[Spastic angina].

The article reports a case of vasospastic angina. The disease is caused by a spasm in a large epicardial coronary artery which may otherwise be normal or show variable degrees of atherosclerosis. The diagnosis must be differentiated from acute myocardial infarction, unstable angina of arteriosclerotic origin and extracardial diseases. ECG may show transient elevation of the ST-segments and coronary arteriography can directly visualize the spasm during a spontaneous attack. Aggressive therapy with calcium antagonists and long-acting nitrates often has an excellent symptomatic effect and may improve the prognosis.

Aged↗