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T Speer

Publications and source records attributed to T Speer.

5 recordsLinked to original sources

Spiral computed tomography-intravenous cholangiography with three-dimensional reconstructions for imaging the biliary tree.

This study aimed to assess the ability of CT-i.v. cholangiography to show the perihilar biliary and cystic duct anatomy and to assess the relative performance of axial, maximum intensity projection and surface rendered displays. We also assessed the correlation between serum bilirubin levels and adequacy of biliary opacification. Spiral CT was carried out following infusion of 100 mL of Biliscopin in 181 patients with suspected biliary disease. The display of biliary anatomy was of high quality, with 91% of patients having good opacification of at least first-order bile ducts and 84% having good opacification of at least third-order right and left hepatic ducts. The quality of biliary opacification correlated inversely to serum bilirubin levels, with levels above two to three times the normal value being associated with lower rates of good opacification. Maximum intensity projection and surface rendered reformats aided anatomical interpretation to a similar degree. The relative frequency of types of perihilar branching patterns and cystic duct junctional anatomy correlated closely to those reported from previous anatomical studies.

Adult↗

Investigation of the patient with abnormal liver function tests.

About one-half of patients with ulcerative colitis develop abnormal liver function tests at some time during the course of the illness. This should prompt an investigation for primary sclerosing cholangitis and other common hepatobiliary diseases. Primary sclerosing cholangitis occurs in 2-10% of patients with ulcerative colitis. The diagnosis of primary sclerosing cholangitis is most often made by endoscopic retrograde cholangiography. Liver histopathology is often inconclusive but magnetic resonance cholangiography shows promise as a useful non-invasive diagnostic tool. Cholangiocarcinoma complicates 20-40% of patients with end-stage primary sclerosing cholangitis and is now one of the most common causes of death in patients with ulcerative colitis. Distinction between benign and malignant strictures can be difficult and is best done with a combination of clinical suspicion, repeated imaging for mass lesions, cholangiography, and endoscopic brushings and/or biopsies. Dominant lesions of the common bile duct or common hepatic duct produce progressive jaundice and liver damage. Early treatment may improve prognosis. Single strictures can be dilated endoscopically. If the stricture is more complicated and extends into the intrahepatic ducts or there is suspicion of cholangiocarcinoma, surgical resection may be more appropriate. Liver transplantation should be considered in end-stage disease.

Bile Duct Diseases↗

The accuracy of preoperative staging for surgically resected laryngeal cancer.

A retrospective analysis was undertaken to evaluate the accuracy of preoperative staging for laryngeal cancers. T (primary tumor) stage was evaluated more accurately by the combined assessment (clinical examination plus computed tomography (CT) for all laryngeal tumors when compared to the clinical examination (75% versus 31%, p less than 0.04). Supraglottic tumors were evaluated more accurately by CT than the clinical examination (86% versus 0%, p less than 0.01). There was no difference between CT and the clinical examination when evaluating glottic and transglottic lesions. The clinical examination, CT and combined assessment equally evaluated N (regional lymph node involvement) stage. The clinical examination and CT are complementary exams that should be used in conjunction when evaluating patients with advanced laryngeal cancers.

Humans↗

Goodbye to paperwork.

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Electronic Data Processing↗