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Biomedical subjects

T Stelmasiak

Publications and source records attributed to T Stelmasiak.

At least 37 records · Page 2Linked to original sources
PubMed1975

Immunoreactive relaxin in human serum during the menstrual cycle.

Immunoreactive relaxin was measured in serum obtained at the same time each day from one woman during a normal menstrual cycle and eight other women using selected bleeding schedules. In addition to relaxin immunoactivity, serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin, estradiol 17beta, and progesterone were measured in the same samples. The data was combined according to the day of the LH peak. Serum relaxin immunoactivity was found to be high over the period of menstruation, its concentration then decreased until the middle of the follicular phase when a peak equal in amplitude to the menstrual peak occurred. Relaxin immunoactivity remained fairly constant throughout the preovulatory LH surge; however, as the LH levels dropped, relaxin immunoactivity increased reaching maximal levels for the whole cycle. Relaxin immunoactivity then increased gradually over the luteal phase and reached a peak when progesterone levels were declining; it then dropped to low levels until menses ensued. It is not possible with the present radioimmunoassay to determine whether the immunoactive relaxin was ovarian or uterine in origin.

Estradiol↗
PubMed1975

Plasma relaxin immunoactivity during the oestrous cycle of the ewe.

Plasma relaxin immunoactivity was measured every 2 hr during 4-day periods in a series of sheep to cover the 17-day period of the ovine oestrous cycle. The immunoactivity fluctuated considerably throughout eacn 4-day period, and a large betwee-animal variation was found. A marked episodic release, occurring at approximately 12.00 and 24.00 hours, was identified and shown to occur more regularly either at certain times of the cycle or in certain animals. Relaxin immunoactivity was high throughout the late pro-oestrous phase of the cycle (Days 15 and 16), and at 24 hr after the onset of the LH peak, conincidnet with the approximate time when ovulation occurs. Bursts of relaxin activity were found on Days 8 to 9 in one ewe, and Days 10 and 11 and 13 to 14 in another. There was no significant correlation between prolactin levels and relaxin immunoactivity in one ewe studied throughout the oestrous period.

Animals↗
PubMedDate not supplied

[Comparison of adrenergic activity in Graves-Basedow disease and in nodular goiter].

The 24-hour urinary excretion of dopamine, noradrenaline and adrenaline was determined in 27 patients with Graves-Basedow disease and 14 patients with hyperactive nodular goitre. The determinations were done before the treatment and after achieving the euthyroid state. The catecholamines were determined by the fluorimetric method which is a modification of the trihydroxyindole method. On the basis of 24-hour excretion of catecholamines with urine the activity of the sympathetic system was compared in both these diseases. No significant differences were found in this 24-hour urinary excretion of catecholamines between both groups. The obtained results suggest a similar degree of adrenergic activity in these two diseases, suggesting thus a secondary character of adrenergic stimulation in hyperthyroidism independently of its causes.

Adult↗