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Biomedical subjects

T Susković

Publications and source records attributed to T Susković.

At least 19 recordsLinked to original sources

Polymyalgia rheumatica--an underdiagnosed disease.

Characteristic features of polymyalgia rheumatica, a widely underdiagnosed disease, are described. The features of the disease are illustrated by the authors' own experience in the treated patients, and compared with literature data. According to the authors' experience, patients with polymyalgia rheumatica are mostly treated for inaccurate diagnoses such as cervicobrachial or lumbosacral syndrome, seronegative rheumatoid arthritis, unexplained febrile state, or precipitated erythrocyte sedimentation rate of unknown etiology. This results is delayed diagnosis or the accurate diagnosis is never reached at all.

Aged↗

[Initial experience with ventilation-perfusion scintigraphy in patients with a suspected pulmonary embolism].

Ventilation-perfusion (V/P) scintigraphy was performed 62 times in 57 patients suspected of having pulmonary embolism (PE). The aim of this study was to present the results and our first experiences in V/P scintigraphy, as well as to point out some specificities of the study. Perfusion scintigraphy was performed following i.v. administration of 99mTc MAA. If the finding was positive, ventilation scan was performed directly after the inhalation of 99mTc DTPA aerosol. Based on the comparison of both findings the patients were divided into four groups: normal finding (8.1% of patients), low (54.8%), medium (22.6%), and high level of PE probability (14.5%). As V/P scintigraphy is a very sensitive and non-aggressive method, it is our opinion that it should be included in PE diagnosing as a "screening" method, because the scanning results greatly influence further therapeutical and diagnostic treatment of the patient.

Adult↗

A female patient with tuberculous polyserositis, and congenital tuberculosis in her new-born child.

A 24-year-old woman was admitted to our department with sepsis, polyserositis and suspected abdominal tumor immediately after delivery. Effusion analyses suggested an etiology of tuberculosis. The severe general condition of the patient allowed for no invasive diagnostic procedures. Antituberculosis therapy was administrated too late and was of no benefit. The fatal outcome was due to septic shock and adult respiratory distress syndrome (ARDS). Autopsy findings confirmed tuberculous polyserositis as well as tuberculous infection of the lungs. The same diagnosis was established in her newborn infant, who responded well to antituberculosis treatment.

Adult↗

Pheochromocytoma without hypertension.

Pheochromocytoma is a rare tumour which is usually suggested by sustained or paroxysmal hypertension. Our patient with a pheochromocytoma was unusual for two reasons: she was normotensive during 3 weeks of close observation in the hospital and the urinary adrenaline level was higher than the noradrenaline level. In the patient's history there were no data on hypertension attacks. The patient had a palpable abdominal mass and the cytological finding was in contrast with a clinical diagnosis of pheochromocytoma. The surgery revealed a tumour and the pathohistologic evaluation established the diagnosis of pheochromocytoma. After surgery, the patient's urinary catecholamine levels reverted to normal. Our patient may have been normotensive because her tumour predominantly secreted adrenaline and perhaps other vasodilating substances.

Adrenal Gland Neoplasms↗

[Systemic allergic vasculitis: case report of a female patient with the Churg-Strauss syndrome].

A female patient with asthmatic attacks developed signs of peripheral and central nervous system involvement, cutaneous and joint manifestations, pulmonary and gastrointestinal involvement, with significant body weight loss. A blood eosinophilia was found and muscle biopsy revealed tissue infiltration by eosinophils and vasculitis. Very short interval from onset of first symptoms to appearance of vasculitis is a bad prognostic sign and probably cause of unsuccessful therapy.

Adult↗

Acute suppurative thyroiditis caused by Salmonella enteritidis.

Acute suppurative thyroiditis in a 47-year-old diabetic woman is reported. Diagnosis was suspected by clinical examination and confirmed by ultrasound, CT-scan and cytological examination. A rare causative agent was isolated--Salmonella enteritidis. No signs of nodular goiter or connection with piriform sinus were found. In spite of our efforts, the source and route of infection remained unclear. However, the haematogenic route seems to be the most plausible. Surgical drainage and antibiotics brought about a complete recovery. Partial lesion of the gland required transitory administration of levothyroxine.

Acute Disease↗

Severe pancreatitis as first symptom of mumps complicated with pseudocyst and abscess of pancreas.

A 22-year-old man, a refugee from Bosnia, developed serious pancreatitis complicated with pseudocyst and pancreatic abscess. Staphylococcus aureus was isolated from pus and blood cultures. On day 12 of illness, parotitis and epididymitis appeared with elevated specific IgG antibody levels to the mumps virus. Surgical drainage and antibiotics were necessary for complete recovery. According to our observations, a significant number of hospitalized refugees during the war in Croatia had impaired host defences probably due to prolonged stress. A negative influence of these circumstances and/or the virulence of the agent should be considered in our patient as well.

Abscess↗

[Cardiac sarcoidosis verified histologically by endovenous myocardial biopsy].

The female patient with sarcoidosis simultaneously involving the lungs, heart, liver, eyes, skin and lacrimal glands is presented. The diagnosis of this disorder was established by biopsy of the liver and skin as well as by at our institution newly introduced method of endovenous blind-myocardial biopsy. Generalized active sarcoidosis had brought the patient into a very profound cachectic state (body weight 48 kg), but her life was directly endangered by granulomatous inflammation of the myocardium with the development of cardiac decompensation, grade I and II atrioventricular conduction disturbances as well as by transitory and total AV block with frequent arrhythmias. A significant resolution of the disease occurred after the introduction of corticosteroid therapy. However, grade I AV block persisted even after one year of treatment, suggesting that the syndrome has probably proceeded from granulomatous inflammation to fibrosis. Therefore, the patient is still a potential candidate for an electrostimulator.

Biopsy, Needle↗

[The HELLP syndrome--a case report].

A 31-year-old secundipara with eclampsia developed the HELLP syndrome after delivery. Clinically, along with very high blood pressure values (29.3/17.3 kPa) and eclamptic attacks, an intense pain in the upper abdomen and nausea were dominant. The patient also had severe thrombocytopenia (18 x 10(9)/L), hemolysis, and increased liver enzymes (SGOT up to 220 U/L and SGPT up to 100 U/L). An intensive therapy, including--together with usual interventions in serious EPH gestoses--also plasmapheresis, antithrombin III substitution, freshly frozen plasma, and transfusion of blood and thrombocytes, proved successful in achieving the normalization of the blood pressure, blood count and liver enzymes, as well as a clinical improvement, so that 18 days after delivery it was possible for the patient to go home, provided with necessary instructions.

Adult↗