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T Tanii

Publications and source records attributed to T Tanii.

29 records · Page 2Linked to original sources
PubMed1986

Opsonic and complement-dependent bactericidal activities of various immunoglobulin preparations for intravenous use.

Some effector functions of various immunoglobulin (IgG) preparations have been compared. Tests for opsonic activity were performed in vitro with human peripheral blood leukocytes and in vivo with mice. The augmentation effects on luminol-dependent chemiluminescence were investigated with human leukocytes. The complement-dependent bactericidal activities were tested with Escherichia coli. Five IgG preparations: pH 4-treated preparation (IG-100), polyethyleneglycol-treated preparation (PEG-G), sulfonated preparation (S-G), pepsin-treated preparation (Pep-G) and a preparation for intramuscular use (GGN) were studied. The results were as follows: (1) IG-100 and PEG-G exhibited strong activities in all test systems; (2) GGN showed a strong opsonic activity; (3) S-G showed relatively weak activities in all test systems, but the revertant S-G preparation exhibited somewhat stronger activities in all systems, and (4) Pep-G showed weak or no activity in all systems. These results suggest that the IgG molecules in IG-100 and PEG-G preparations have satisfactory effector functions. On the other hand, IgG molecules in S-G and Pep-G preparation may have significant deficiencies in their biological functions.

Animals↗
PubMed1985

Increase of mast cells in the alopecia lesion of mice.

A histological investigation was made of the quantitative behavior of mast cells in bald areas on mice and in human alopecia areata. C57BL,W/Wv and +/+ mice with alopecia lesions were examined. In C57BL mice and +/+ mice, the number of dermal mast cells (per square mm) in the bald areas was greater than that in controls. The mean number of mast cells was slightly higher in human alopecia areata than in the controls. Since W/Wv mice lacking mast cells developed alopecia lesions, it seems that mast cells are not necessary for the onset of alopecia areata but could play some part in regrowth.

Alopecia Areata↗
PubMed1984

A variant of encephalomeningocele: heterotopic brain tissue on the scalp.

A 2-year-old girl having a bald nodule on the scalp is reported. The tumor was circular, hemispherically elevated and had a dull reddish color. Roentgenologic studies revealed a defect of the underlying skull bone, and spina bifida occulta on the first and second sacral vertebra were found. Craniotomy was carried out. The tumor extended into the falx cerebri and reached to the tentorium cerebelli, and was not connected with the cerebrum. Histological examination showed insular brain tissue containing glial cells in the lower dermis. Around this tissue, there seemed to be vascular leptomeninges with numerous melanocytes and thickened fibrous elements, probably dura. From these findings, this case was diagnosed as a variant of encephalomeningocele, and as melanocytes physiologically exist on the leptomeninges, melanocytes in an encephalomeningocele may diagnostically identify the leptomeninges.

Calcinosis↗
PubMed1984

Mondor's phlebitis of the penis: a study with factor VIII related antigen.

Four patients with so-called non-venereal sclerosing lymphangitis of the penis are reported. It was suggested that the affected vessels were veins by positively stained factor VIII related antigen with the unlabeled peroxidase-antiperoxidase method. If cord-like linear subcutaneous swelling observed in the coronary sulcus or dorsal region of the penile shaft originate from the vein, it seems correct to call this disease as Mondor's phlebitis of the penis.

Adult↗
PubMed1982

Antigenicity of beta-lactam antibiotic preparations: production of IgE antibodies to beta-lactam antibiotic and their cross-reaction within the antibiotic group.

BALB/C mice were immunized with conjugate of benzylpenicillin or ampicillin with Ascaris suum extract. The mice developed IgE antibodies to penicillin, which were found to react with commercially available penicillin preparations in the PCA system. Elimination of polymerized penicillin by Sephadex chromatography from tested preparations could not diminish their activities to elicit PCA. High pressure liquid chromatographic (HPLC) separation of PcG preparation yielded fractions unable to elicit PCA. On the other hand, all fractions from ABPC retained the activity even after the HPLC purification. A comparative estimation of cross-reactivity of IgE and IgE antipenicillin antibodies showed that IgE antibodies cross-reacted with a variety of beta-lactam antibiotics in a high degree.

Ampicillin↗
PubMed1981

Chemical screening of radiation protecting agents.

An aqueous solution of 2-propanol was chosen as chemical system for fundamental study of the chemical screening of organic compounds on the responsibility for ionizing radiation. The effect of additives on the yield of acetone was investigated by subjecting this system on gamma-radiolysis. The results show that this system is suitable for the estimation of radiation protecting character of the known radiation protecting agents and compounds which act as a OH scavenger. On the basis of these results, various nitrogen-containing additives having free amino group, guanidine group and hetero-cyclic amine were examined first of all in expectation of improvement for the toxicity of sulfur-containing compounds.

1-Propanol↗