Biomedical subjects

T Taschev

Publications and source records attributed to T Taschev.

12 recordsLinked to original sources

PubMed1978

[Effects of reduced diet and physical stress on liver lysosomes. Morphological and biochemical studies].

Groups of 15 rats each (I--non-reduced diet; II--non-reduced diet and physical stress; III--diet reduced by 40%; IV--reduced diet and physical stress) were examined after 20 and 140 days, respectively. The electron microscopic examination revealed that the most important changes had occurred in group III; there exists an excess of autophagolysosomes. The biochemical examinations show that the reduced diet (group III) also produces a considerable increase in activity of most of the lysosome enzymes in the liver. The occurrence of autophagy evidences that this is either physiologically induced or the manifestation of a beginning pathological process.

Aging↗

PubMed1978

[Relationship between diet and some risk factors].

The authors evaluated data from the dietary histories of 203 individuals from Sofia and Varna who had been asked identical questions. The results of this investigation show that 42% of these these individuals have no marked liking for a certain diet (group 1), 28% prefer a high protein diet (group 2), 23% are partial to a high carbohydrate diet (group 3), and 6% give preference to a high fat diet (group 4). It was found that the individuals in group 1 showed the smallest deviations from the normal values for serum lipids. Coronary symptoms were most marked in the individuals in group 4, followed by those in the groups 3, 2 and 1. It was stated that men prefer a high protein diet to a greater extent than women. Consumers of alcohol and smokers have no liking for a high carbohydrate diet. Individuals prefering fats and a high carbohydrate diet lack a daily dietary rhythm. The latter also showed marked variations in body weight, i.e., periods of weight reduction and periods of weight increase. The most favourable findings with regard to serum lipids, body weight and dietary rhythm were obtained from individuals with obvious preference for a certain diet, i. e., those with a balanced diet. The present investigation is suited as a model for a more comprehensive epidemiological study.

Bulgaria↗

PubMed1977

[Paradoxes in the clinical aspects of depression (author's transl)].

An attempt is made to present the contradictions in the clinical picture of depression as "paradoxes". 12 of these are briefly reported. In the author's opinion, they are, on the one hand, the sequel to a sudden lowering of bio-energetic potential of the patient and on the other, caused by the maintained formal logic of his consciousness. Some of these paradoxes, although again rooted in the behavior of the patient, are chiefly seen as such in the consciousness of the doctor because the doctor is accustomed to having a different image of the depressed patient. The opinion is expressed that pathophysiological phase symptoms in the activity of the cerebral cortex (in the Pavlovian sense) are responsible for the nature of these paradoxes which are, to a certain extent, understandable psychologically.

Anxiety↗

PubMed1976

[Comparative investigations of psychoses in parents, children and siblings (author's transl)].

Psychoses in 441 hospital patients from 210 families have been investigated comparatively. In 106 families 109 parents and 117 children suffer as do 215 siblings in 104 families. It has been established that the sexual appurtenance does not have a decisive importance in the genetic transmission of the psychoses, while comparing the diagnoses, a high percentage (84.5%) of coincidence is founded. Similarities appear in the clinical features, in their course, and the therapeutical effect. The psychoses begin at an earlier age and are taking a heavier course in children, when compared to parents and in the younger brothers and sisters when compared to the elder. In couples with different diagnoses, a similarity is determined as far as the investigated indices are concerned. The clinical features are atypical and symptoms and syndromes, characteristic for the different families, are manifested.

Adjustment Disorders↗

PubMed1973